69821-03-0

Basic information

• Product Name: 1,3-Dioxolane, 4-[2-(2,5-dimethoxy-3,4,6-trimethylphenyl)ethyl]-2,2,4-trimethyl-, (4S)-
• CAS NO: 69821-03-0
• Molecular Formula: C19H30O4
• Molecular Weight: 322.445
• Mol File: 69821-03-0.mol

Chemical Properties

• CAS DataBase Reference: 1,3-Dioxolane, 4-[2-(2,5-dimethoxy-3,4,6-trimethylphenyl)ethyl]-2,2,4-trimethyl-, (4S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dioxolane, 4-[2-(2,5-dimethoxy-3,4,6-trimethylphenyl)ethyl]-2,2,4-trimethyl-, (4S)-(69821-03-0)
• EPA Substance Registry System: 1,3-Dioxolane, 4-[2-(2,5-dimethoxy-3,4,6-trimethylphenyl)ethyl]-2,2,4-trimethyl-, (4S)-(69821-03-0)

Safety Data

• Hazardous Substances Data: 69821-03-0(Hazardous Substances Data)

Upstream product

• 85148-25-0 (S)-4-(2',5'-dimethoxy-3',4',6'-trimethylphenyl)-2-methyl-1,2-butanediol 
• 77-76-9 2,2-dimethoxy-propane 
• 67-64-1 acetone 
• 73127-73-8 2,5-dimethoxy-3,4,6-trimethylphenylmagnesium bromide 
• 136025-65-5 (S)-(+)-3,4-dibenzyloxy-4-methyl-1-butanol 
• 136025-66-6 (S)-3,4-Bis-benzyloxy-3-methyl-butyraldehyde 
• 96203-92-8 (E)-4-(2,5-dimethoxy-3,4,6-trimethylcyclohexa-1,5-dienyl)-2-methylbut-2-en-1-ol 
• 96203-90-6 (2R,3R)-4-(2',5'-dimethoxy-3',4',6'-trimethylphenyl)-2,3-epoxy-2-methylbutanol 
• 1838-94-4 isoprene epoxide 
• 85148-24-9 (S)-4-(2,5-dimethoxy-3,4,6-trimethylphenyl)-2-hydroxy-2-methylbutanal 
• 85148-23-8 3-(2,5-Dimethoxy-3,4,6-trimethyl-phenyl)-1-((S)-2-phenyl-hexahydro-pyrrolo[1,2-c]imidazol-3-yl)-propan-1-one 

Downstream Products

• 69371-84-2 (S)-2-methyl-4-(3,5,6-trimethyl-1,4-benzoquinon-2-yl)-butane-1,2-diol 
• 69821-04-1 (3S,9aR)-(-)-3,6,8,9-tetramethyl-3,9a-epoxy-2,3,4,5,7,9a-hexahydro-1-benzoxepin-1-one 

Relevant articles and documents

A Synthesis of Natural α-Tocopherol Intermediate

(S)-(-)-6-Hydroxy-2,5,7,8-tetramethyl-2-chromanmethanol, an intermediate of natural α-tocopherol was synthesized from (S)-2-benzyloxy-2-methyl-4-pentenoic acid, which was obtained by the enzymatic hydrolysis of the corresponding racemic methyl ester.

AN EFFICIENT SYNTHESIS OF (S)-CHROMANMETHANOL, A VITAMIN E PRECURSOR

The (S)-chromanmethanol, a key intermediate for the synthesis of optically active α-tocopherol was synthesized by a reaction sequence which utilized the asymmetric epoxidation of the (E)-allylic alcohol to the (2R,3R)-epoxyalcohol in high enantiomeric exc

ASYMMETRIC SYNTHESIS OF A CHROMAN DERIVATIVE (VITAMIN E PRECURSOR)

Chromanmethanol 2, a chiral intermediate for the synthesis of α-tocopherol 1, is prepared from α-hydroxy aldehyde 5, which is obtained by an asymmetric synthesis in over 95percent ee.

Synthesis of (S)-(+)-6-hydroxy-2,5,7,8-tetramethylchroman-2-methanol and intermediates therein

A process if disclosed for producing (S)-(+)-6-hydroxy-2,4,7,8-tetramethylchroman-2-methanol from either alkyl(R)-2-benzyloxy-3-hydroxy-2-methyl-propionate or (S)-2,2,4-trimethyl-1,3-dioxolan-4-ethanol including intermediates in this synthesis.