69830-86-0Relevant academic research and scientific papers
CHARACTERISTICS OF VELLOSIMINE REDUCTASE, A SPECIFIC ENZYME INVOLVED IN THE BIOSYNTHESIS OF THE RAUWOLFIA ALKALOID SARPAGINE
Pfitzner, Artur,Krausch, Brigitte,Stoeckigt, Joachim
, p. 1691 - 1700 (1984)
A plant enzyme - vellosimine reductase - has been isolated from Rauwolfia cell suspension cultures.This new enzyme has been purified (110-fold) and characterized.The reductase is a specific enzyme of the sarpagine pathway catalyzing the NADPH dependent conversion of vellosimine into 10-deoxysarpagine.The latter alkaloid is the immediate biogenetic precursor of sarpagine as shown by its high in vivo incorporation rate (86percent) into sarpagine.
STRUCTURE OF PELIRINE AND CHEMICAL CONVERSION OF GARDNERINE TO 11-METHOXY-16-EPIAFFININE
Wan, Alfred S. C.,Yokota, Masaki,Ogata, Koreharu,Aimi, Norio,Sakai, Shin-ichiro
, p. 1211 - 1214 (2007/10/02)
The structure of pelirine, isolated from roots of Rauwolfia perakensis was shown to be 10-methoxyepiaffinine by comparison with the spectral data of 11-methoxyepiaffinine which was synthesized from the known alkaloid gardnerine.The proposed structure has been confirmed by X-ray crystallography.
