Tetrahedron p. 1691 - 1700 (1984)
Update date:2022-07-31
Topics:
Pfitzner, Artur
Krausch, Brigitte
Stoeckigt, Joachim
A plant enzyme - vellosimine reductase - has been isolated from Rauwolfia cell suspension cultures.This new enzyme has been purified (110-fold) and characterized.The reductase is a specific enzyme of the sarpagine pathway catalyzing the NADPH dependent conversion of vellosimine into 10-deoxysarpagine.The latter alkaloid is the immediate biogenetic precursor of sarpagine as shown by its high in vivo incorporation rate (86percent) into sarpagine.
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