69850-56-2Relevant academic research and scientific papers
Efficient synthesis of β-amino-α,β-unsaturated carbonyl compounds
Zhao, Yuanhong,Zhao, Jingfeng,Zhou, Yongyun,Lei, Ze,Li, Liang,Zhang, Hongbin
, p. 769 - 772 (2005)
A versatile and high-yielding procedure for the synthesis of β-enamino esters and β-enaminones is presented: in the presence of tetraethyl orthosilicate, a number of highly functional β-enamino esters were obtained; this method provided an alternative for the formation of β-amino-α,β-unsaturated carbonyl compounds with mild and functional group compatible reaction conditions. The Royal Society of Chemistry and the Centre National de la Recherche Scientifique 2005.
ENAMINE CHEMISTRY, PART XXI. N- AND/OR C-SUBSTITUTION (ALKYLATION, ACYLATION) OF ETHYL 3-AMINO-2-BUTENOATE. THE PREPARATION OF 2-SUBSTITUTED 4-METHYL-1,3-THIAZINE-6-THIONES
Shabana, R.,Rasmussen, J. B.,Lawesson, S.-O.
, p. 75 - 82 (2007/10/02)
Alkylation of ethyl 3-amino-2-butenoate, 1, with methyl iodide, ethyl iodide, and benzyl bromide gave both C- and N-alkylated products (contrary to earlier findings) the ratio of which was determined by GLC.Methylation of 1 was studied under different con
