69872-15-7

Basic information

• Product Name: 3-Bromo-4-methyl-5-nitropyridine
• Synonyms: 3-Bromo-4-methyl-5-nitropyridine;3-Bromo-4-methy-5nitro-pyridine
• CAS NO: 69872-15-7
• Molecular Formula: C₆H₅BrN₂O₂
• Molecular Weight: 217.0201
• Product Categories: Heterocycle-Pyridine series
• Mol File: 69872-15-7.mol
• Article Data: 8

Chemical Properties

• Melting Point: 57-58℃
• Boiling Point: 269℃
• Flash Point: 116℃
• Appearance: /
• Density: 1.709
• Vapor Pressure: 0.013mmHg at 25°C
• Refractive Index: 1.6
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: -0.51±0.28(Predicted)
• CAS DataBase Reference: 3-Bromo-4-methyl-5-nitropyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Bromo-4-methyl-5-nitropyridine(69872-15-7)
• EPA Substance Registry System: 3-Bromo-4-methyl-5-nitropyridine(69872-15-7)

Safety Data

• Hazardous Substances Data: 69872-15-7(Hazardous Substances Data)

Usage

Uses

3-Bromo-4-methyl-5-nitropyridine is an intermediate used in the synthesis of 4-bromo-6-azaindole and other azaindole derivatives.

InChI:InChI=1/C6H5BrN2O2/c1-4-5(7)2-8-3-6(4)9(10)11/h2-3H,1H3

Upstream product

• 31872-63-6 3-bromo-4-chloro-5-nitropyridine 
• 31872-65-8 3-bromo-5-nitropyridin-4-ol 
• 5435-54-1 4-hydroxy-3-nitropyridine 
• 105-53-3 diethyl malonate 
• 69872-14-6 diethyl 2-(3-bromo-5-nitro-4-pyridyl)propanedioate 

Downstream Products

• 627510-77-4 3-bromo-5-nitro-4-[(E)-2-phenylethenyl]pyridine 
• 627510-81-0 4-bromo-2-phenyl-1H-pyrrolo[2,3-c]pyridine 
• 627510-83-2 4-bromo-2-phenyl-1H-pyrrolo[2,3-c]pyridin-1-ol 
• 850892-12-5 5-bromo-4-methylpyridin-3-amine 
• 850892-97-6 tert-butyl 4-bromo-1H-pyrrolo[2,3-c]pyridine-1-carboxylate 
• 69872-17-9 4-bromo-1H-pyrrolo[2,3-c]pyridine 
• 1578264-55-7 C₁₈H₁₆FN₃O₃ 
• 1578264-53-5 C₁₈H₁₆FN₃O₃ 
• 1578264-54-6 C₁₈H₁₆FN₃O₃ 
• 1578264-56-8 C₁₈H₁₆FN₃O₃ 
• 1578264-57-9 C₁₈H₁₆FN₃O₃ 
• 1086392-42-8 ethyl 4-bromo-1H-pyrrolo[2,3-c]pyridine-2-carboxylate 

Relevant articles and documents

SUBSTITUTED 5-CYANOINDOLE COMPOUNDS AND USES THEREOF

A compound of Formula (I), or a pharmaceutically acceptable salt thereof, is provided that has been shown to be useful for the treatment of lysine (K)-specific demethylase 1A (LSD1) - mediated diseases or disorders, Formula (I), wherein R1, R2, R3, R4, and R5 are as defined herein.

Azaindolines: Derisking the indoline structural alert

4-Substitued azaindolines, which are isosteres of indolines, are useful synthetic building blocks that reduce the risk of bioactivation induced idiosyncratic toxicity have been prepared. Multigram routes to 2,3-dihydro-1H-pyrrolo[2,3-c]pyridine-4-triflate 16, 2,3-dihydro-1H-pyrrolo[2,3- b]pyridine-4-carbonitrile 20 and 4-chloro-2,3-dihydro-1H-pyrrolo[2,3-d] pyridazine 30 are outlined.