69897-47-8 Usage
Uses
Used in Pharmaceutical and Medicinal Chemistry:
(S)-2-hydroxy-3-phenylpropanamide is used as a starting material for the synthesis of various pharmaceuticals and biologically active compounds due to its unique structure and properties.
Used as a Chiral Auxiliary in Asymmetric Synthesis:
(S)-2-hydroxy-3-phenylpropanamide is employed as a chiral auxiliary in asymmetric synthesis, which is crucial for the production of enantiomerically pure compounds, often required for the desired biological activity and to avoid potential side effects of the racemic mixture.
Used in Drug Development:
(S)-2-hydroxy-3-phenylpropanamide serves as a building block for the development of new drugs, contributing to the advancement of pharmaceutical research and the creation of novel therapeutic agents.
Used in Organic Synthesis:
(S)-2-hydroxy-3-phenylpropanamide is utilized in organic synthesis for the preparation of a range of chemical products, highlighting its versatility and importance in the field of chemistry.
Used in Research and Development of Anti-inflammatory and Neuroprotective Agents:
(S)-2-hydroxy-3-phenylpropanamide is used as a subject of study for its potential anti-inflammatory and neuroprotective properties, with the aim of developing new treatments for various inflammatory and neurodegenerative conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 69897-47-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,9,8,9 and 7 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 69897-47:
(7*6)+(6*9)+(5*8)+(4*9)+(3*7)+(2*4)+(1*7)=208
208 % 10 = 8
So 69897-47-8 is a valid CAS Registry Number.
69897-47-8Relevant articles and documents
Synthesis of Peptidosulfinamides and Peptidosulfonamides: Peptidomimetics Containing the Sulfinamide or Sulfonamide Transition-State Isostere
Moree, Wilna J.,Marel, Gijs A. van der,Liskamp, Rob J.
, p. 5157 - 5169 (2007/10/02)
Synthetic routes are described toward the preparation of α- as well as β-substituted aminoethanesulfinyl chlorides, starting from either an aldehyde or from an amino acid derivative.The sulfinyl chlorides are used as building blocks for the preparation of homochiral α- or β-substituted sulfinamide and sulfonamide transition-state isosteres.The methodology has been applied to the synthesis of peptidosulfonamide peptidomimetics such as a hapten needed for the generation of antibodies and potential HIV protease inhibitors.In addition, the β-substituted aminoethanesulfinyl chlorides were used as building blocks for the preparation of a tetrapeptidosulfonamide, which can be considered as a biopolymer mimetic, employing a repetition of a cycle of three reactions: coupling of the sulfinyl chloride to the N-terminus of the growing peptidosulfonamide, oxidation to the sulfonamide, and deprotection of the N-terminus.
