69992-13-8Relevant academic research and scientific papers
Improved synthesis of an ascaroside pheromone controlling dauer larva development in caenorhabditis elegans
Martin, Rene,Schaefer, Tina,Theumer, Gabriele,Entchev, Eugeni V.,Kurzchalia, Teymuras V.,Knoelker, Hans-Joachim
experimental part, p. 3488 - 3492 (2010/03/02)
Using an efficient Wacker oxidation as a key step, we describe a significantly improved synthesis of the dauer-promoting ascaroside 2 for biological studies of the novel sterol ring methylase STRM-1.
6R-(3,6-DIDEOXY-L-ARABINO-HEXOPYRANOSYLOXY)HEPTANOIC ACID, PREPARATION PROCESS FOR THE SAME AND DAUER EFFECT THEREOF
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Page/Page column 5; 11-12, (2008/06/13)
The present invention relates to a determination of a stereochemistry, a synthesis and dauer effect of 6R-(3,6-dideoxy-L-arabino-hexopyranosyloxy) heptanoic acid as a pheromone isolated from the Caenorhabditis elegance related to suppress of aging and
Synthesis of stereospecifically labeled 3,6-dideoxyhexoses.
Russell,Weigel,Han,Liu
, p. 95 - 114 (2007/10/02)
Preparations of ascarylose (3,6-dideoxy-L-arabino-hexose), abequose (3,6-dideoxy-D-xylo-hexose), and paratose (3,6-dideoxy-D-ribo-hexose) with stereospecific deuterium labeling at C-3 are discussed. The methods used to synthesize these sugars, such as the
SYNTHESIS OF STEREOSPECIFICALLY LABELED CARBOHYDRATES: PREPARATION OF (3S)- AND (3R)-ASCARYLOSE
Han, Oksoo,Liu, Hung-wen
, p. 1073 - 1076 (2007/10/02)
The general problem of the synthesis of 3,6-dideoxy sugars containing stereospecifically labeled hydrogen isotope at C-3 is adressed for the specific case of ascarylose (3,6-dideoxy-L-arabino-hexose).
β-ELIMINATION IN ALDONOLACTONES. THE CONVERSION OF L-RHAMNONO-1,5-LACTONE INTO 3-BENZOYLOXY-6-METHYLPYRAN-2-ONE
Varela, Oscar J.,Cirelli, Alicia Fernandez,Lederkremer, Rosa M. de
, p. 219 - 224 (2007/10/02)
Benzoylation of L-rhamnono-1,5-lactone (1) for 90 min at room temperature afforded 2,3,4-tri-O-benzoyl-L-rhamnono-1,5-lactone (2).When an excess of benzoyl chloride and pyridine was used for 20 h, with subsequent sublimation of benzoic acid from the mixture at 120 deg C in vacuo, a double elimination took place and 3-benzoyloxy-6-methylpyran-2-one (4) was isolated as the main product.The conversion of 1,2, and 2,4-di-O-benzoyl-3,6-dideoxy-L-erythro-hex-2-enono-1,5-lactone (3) into the pyran-4-one derivative 4 under different conditions was monitored chromatographically.
