70-57-5

Basic information

• Product Name: 5-METHYLNICOTINAMIDE
• Synonyms: 5-METHYLPYRIDINE-3-CARBOXAMIDE;5-METHYLNICOTINAMIDE;3-Pyridinecarboxamide,5-methyl-(9CI);5-Methyl-3-PyridinecarboxaMide
• CAS NO: 70-57-5
• Molecular Formula: C₇H₈N₂O
• Molecular Weight: 136.15
• EINECS: -0
• Product Categories: AMIDE;Pyridines
• Mol File: 70-57-5.mol
• Article Data: 7

Chemical Properties

• Melting Point: 166-168°C
• Boiling Point: 290 °C at 760 mmHg
• Flash Point: 129.2 °C
• Appearance: /
• Density: 1.157g/cm³
• Vapor Pressure: 0.00213mmHg at 25°C
• Refractive Index: 1.561
• Storage Temp.: 2-8°C
• Solubility: DMSO (Slightly), Methanol (Slightly)
• BRN: 4962976
• CAS DataBase Reference: 5-METHYLNICOTINAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-METHYLNICOTINAMIDE(70-57-5)
• EPA Substance Registry System: 5-METHYLNICOTINAMIDE(70-57-5)

Safety Data

• Safety Statements: 22-24/25
• Hazardous Substances Data: 70-57-5(Hazardous Substances Data)

Usage

Uses

5-Methylnicotinamide can be used to treat necrotizing enterocolitis.

InChI:InChI=1/C7H8N2O/c1-5-2-6(7(8)10)4-9-3-5/h2-4H,1H3,(H2,8,10)

Upstream product

• 591-22-0 3,5-Lutidine 
• 3222-49-9 5-methylnicotinic acid 
• 20826-02-2 ethyl 5-methyl-3-pyridinecarboxylate 
• 884494-95-5 5-methyl-nicotinic acid chloride 

Downstream Products

• 3430-19-1 5-methylpyridin-3-amine 
• 445041-06-5 C₂₆H₂₃Cl₂N₂O₆⁽¹⁺⁾ 
• 114995-63-0 (2-Amino-3,5-difluoro-phenyl)-(5-fluoro-pyridin-3-yl)-methanone 
• 22620-32-2 (5-fluoropyridin-3-yl)methanol 
• 39891-04-8 5-fluoropyridine-3-carboxaldehyde 
• 455-70-9 5-fluoro-3-pyridinecarboxylic acid methyl ester 
• 42885-14-3 5-cyano-3-methylpyridine 
• 177660-92-3 4-[2-(5-methylpyridin-3-yl)-4-(trifluoromethyl)-1H-imidazol-1-yl]benzenesulfonamide 
• 177660-88-7 3-methyl-5-[1-[4-(methylsulfonyl)phenyl]-4-(trifluoromethyl)-1H-imidazol-2-yl]pyridine 

Relevant articles and documents

COMPOUNDS AND USE THEREOF IN THE EXPANSION OF STEM CELLS AND/OR PROGENITOR CELLS

The invention relates to compounds of formula I and pharmaceutical compositions containing them. Also, the invention relates to methods for expanding stem cells and/or progenitor cells and methods for treating a hematopoietic disorder/malignancy, and autoimmune disease and/or an inherited immunodeficient disease (I).

SULFONYL AMIDE DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELL GROWTH

The present invention relates to a compound of the formula I wherein R1 to R6, A, B, n and m are as defined herein. Such novel sulfonyl amide derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. This invention also relates to a method of using such compounds in the treatment of abnormal cell growth in mammals, especially humans, and to pharmaceutical compositions containing such compounds.

1,2-aryl and heteroaryl substituted imidazolyl compounds for the treatment of inflammation

A class of imidazolyl compounds is described for use in treating inflammation and inflammation-related disorders. Compounds of particular interest are defined by Formula I: STR1 wherein R1 -R6 are as described in the specification; or a pharmaceutically-acceptable salt thereof.