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Norephedrine, also known as phenylpropanolamine or PPA, is a sympathomimetic amine that functions as a stimulant and decongestant. It is structurally similar to ephedrine and pseudoephedrine, and was once widely used in over-the-counter medications for treating colds, allergies, and attention deficit hyperactivity disorder (ADHD). However, due to its potential side effects, including increased blood pressure and heart rate, as well as links to hemorrhagic stroke, the use of norephedrine has been restricted or banned in many countries. It is now considered a controlled substance in some regions, and its use is limited to specific medical applications under strict supervision.

700-65-2

700-65-2 Suppliers

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700-65-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 700-65-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 7,0 and 0 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 700-65:
(5*7)+(4*0)+(3*0)+(2*6)+(1*5)=52
52 % 10 = 2
So 700-65-2 is a valid CAS Registry Number.

700-65-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name (1S,2R)-2-amino-1-phenylpropan-1-ol

1.2 Other means of identification

Product number -
Other names phenylpropanolamine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:700-65-2 SDS

700-65-2Relevant academic research and scientific papers

Charge-transfer interactions: An efficient tool for recycling bis(oxazoline)-copper complexes in asymmetric henry reactions

Didier, Dorian,Magnier-Bouvier, Caroline,Schulz, Emmanuelle

supporting information; experimental part, p. 1087 - 1095 (2011/07/09)

An anthracenyl-modified chiral bis(oxazoline) copper complex has been demonstrated to efficiently promote nitroaldol reactions between structurally varying aldehydes and nitromethane or nitroethane. The catalyst was recovered through formation of a charge transfer complex between the chiral ligand and trinitrofluorenone and its subsequent precipitation with pentane. The efficiency of this procedure was proved through several consecutive catalytic cycles that allowed the sturdy formation of the expected product with a high enantioselectivity. The catalyst′s stability was also put to the test in an original multi-substrate procedure. Following the same recovery concept, a new heterogeneous procedure was tested for which trinitrofluorenone was covalently linked to a silica support. Asymmetric heterogeneous catalysis was performed under these conditions as one of the few examples demonstrating the potential catalyst recycling in nitroaldol reactions through reversible, non-covalent interactions. Copyright

Stereoselectrive Syntheses of Ephedrine and Related 2-Aminoalcohols of High Optical Purity from Protected Cyanohydrins

Jackson, W. Roy,Jacobs, Howard A.,Matthews, Barry R.,Jayatilake, Gamini S.,Watson, Keith G.

, p. 1447 - 1450 (2007/10/02)

Ephedrine and related optically active β-aminoalcohols can be prepared by zinc borohydride reduction of aryl O-protected magnesium imines and aryl α-hydroxyimimes which in turn are readily available from optically active cyanohydrins.

β-Amino alcohols from amino acids: Chelation control via Schiff bases

Polt,Peterson

, p. 4985 - 4986 (2007/10/02)

Sequential addition of iBu2AlH and RLi or RMgX to Schiff base esters derived from amino acids provides a simple route to β-amino alcohols. The reaction procedes without racemization, and with high threo selectivity. Several representative sphingosines are synthesized.