70001-26-2

Upstream product

• 330823-63-7 C₃₂H₃₉NO₁₄ 
• 150607-94-6 methyl 1,2,3,4-tetra-O-isobutyryl-β-D-glucopyranuronate 
• 302965-12-4 4,5-epoxy-17-methyl-(5α,6α)-morphinan-3,6-diol 3-benzoate 
• 302965-10-2 Methyl (phenyl 2,3,4-tri-O-isobutyryl-1-thio-β-D-glucopyranosid)uronate 
• 509-60-4 dihydromorphine 
• 330823-61-5 3-O-methoxycarbonyl dihydromorphine 
• 57820-69-6 (3R,4S,5S,6S)-2-bromo-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate 
• 302965-08-8 C₄₃H₅₃NO₁₃ 

Relevant academic research and scientific papers

Selective synthesis of both isomers of morphine 6-β-D-glucuronide and their analogs

A stereoselective synthesis of both isomers of the pharmaceutically important morphine 6-β-D-glucuronide (M6G) and its analogs was developed. The method is based on the use of ZnBr2 for the key coupling reaction. It was shown that the α/β stere

6-O-Glycosylation of morphine derivatives using thioglycosides as glycosyl donors

A novel approach was developed for the synthesis of the pharmaceutically important morphine and dihydromorphine 6-β-D-glucuronides. The key step involves a selective 6-O-glycosylation of 3-O-protected morphines and dihydromorphines with thioglycosides that serve as glycosyl donors in the presence of thiophilic promoters. This novel approach may be useful for the O-glycosylation of other alkoloid derivatives.