700380-75-2Relevant articles and documents
Enzymatic synthesis of optically active α-chloro-δ-hydroxy- β-ketoalkanephosphonates and reactions thereof
Xu, Chengfu,Yuan, Chengye
, p. 3883 - 3892 (2007/10/03)
A novel and enzymatic approach to α-chloro-δ-hydroxy-β- ketoalkanephosphonates was developed via enantioselective CALB-catalyzed acetylation and CRL-catalyzed hydrolysis. The resultant optically active compounds provide, via Horner-Wadsworth-Emmons (HWE)
A new reaction system for Horner-Wadsworth-Emmons olefination of optically active 4-hydroxy-2-oxo-alkylphosphonates and 4-hydroxy-1-chloro-2-oxo- alkylphosphonates with aliphatic aldehydes
Xu, Chengfu,Yuan, Chengye
, p. 2449 - 2458 (2007/10/03)
A new and convenient reaction system is described for the synthesis of chiral β′-hydroxy-α,β-unsatuarated ketones based on the Horner-Wadsworth-Emmons olefination of optically active 4-hydroxy-2-oxo- alkylphosphonates and 4-hydroxy-l-chloro-2-oxo-alkylpho