700380-65-0Relevant articles and documents
Enzymatic synthesis of optically active α-chloro-δ-hydroxy- β-ketoalkanephosphonates and reactions thereof
Xu, Chengfu,Yuan, Chengye
, p. 3883 - 3892 (2007/10/03)
A novel and enzymatic approach to α-chloro-δ-hydroxy-β- ketoalkanephosphonates was developed via enantioselective CALB-catalyzed acetylation and CRL-catalyzed hydrolysis. The resultant optically active compounds provide, via Horner-Wadsworth-Emmons (HWE)