70059-35-7

Upstream product

• 369-32-4 1-(4-fluoro-3-methylphenyl)ethanone 
• 100-63-0 phenylhydrazine 

Downstream Products

• 77445-15-9 Diethyl-[2-(4-fluoro-3-methyl-phenyl)-1H-indol-3-ylmethyl]-amine 
• 131520-50-8 5-[2-(4-Fluoro-3-methyl-phenyl)-1H-indol-3-ylmethylene]-pyrimidine-2,4,6-trione 
• 131520-57-5 5-[2-(4-Fluoro-3-methyl-phenyl)-1H-indol-3-ylmethylene]-2-thioxo-dihydro-pyrimidine-4,6-dione 
• 109272-15-3 2-{[1-[2-(4-Fluoro-3-methyl-phenyl)-1H-indol-3-yl]-meth-(Z)-ylidene]-hydrazono}-5-[1-pentafluorophenyl-meth-(E)-ylidene]-thiazolidin-4-one 
• 109272-13-1 2-{[1-[2-(4-Fluoro-3-methyl-phenyl)-1H-indol-3-yl]-meth-(Z)-ylidene]-hydrazono}-5-[1-(4-nitro-phenyl)-meth-(E)-ylidene]-thiazolidin-4-one 
• 109272-16-4 5-[1-Benzo[1,3]dioxol-5-yl-meth-(E)-ylidene]-2-{[1-[2-(4-fluoro-3-methyl-phenyl)-1H-indol-3-yl]-meth-(Z)-ylidene]-hydrazono}-thiazolidin-4-one 
• 109272-14-2 2-{[1-[2-(4-Fluoro-3-methyl-phenyl)-1H-indol-3-yl]-meth-(Z)-ylidene]-hydrazono}-5-[1-(4-fluoro-phenyl)-meth-(E)-ylidene]-thiazolidin-4-one 
• 109271-96-7 C₁₇H₁₅FN₄S 
• 77445-70-6 1-[2-(4-Fluoro-3-methyl-phenyl)-1H-indol-3-yl]-2-(4-{2-[2-(4-fluoro-3-methyl-phenyl)-1H-indol-3-yl]-2-oxo-acetyl}-piperazin-1-yl)-ethane-1,2-dione 
• 77445-51-3 1-[2-(4-Fluoro-3-methyl-phenyl)-1H-indol-3-yl]-2-morpholin-4-yl-ethane-1,2-dione 
• 77445-52-4 1-[2-(4-Fluoro-3-methyl-phenyl)-1H-indol-3-yl]-2-piperidin-1-yl-ethane-1,2-dione 
• 77445-79-5 2-(4-Fluoro-3-methyl-phenyl)-3-(2-morpholin-4-yl-ethyl)-1H-indole 
• 77445-49-9 N,N-Diethyl-2-[2-(4-fluoro-3-methyl-phenyl)-1H-indol-3-yl]-2-oxo-acetamide 
• 77445-50-2 2-[2-(4-Fluoro-3-methyl-phenyl)-1H-indol-3-yl]-N,N-dimethyl-2-oxo-acetamide 

Relevant academic research and scientific papers

Simple indole synthesis by one-pot sonogashira coupling-NaOH-mediated cyclization

Coupling of o-iodoanilines with terminal alkynes under standard Sonogashira conditions, and further treatment with NaOH under conventional heating or microwave irradiation, afford 2-substituted indoles in usually high yields. Functionalities such as halides, nitro, and cyano groups are tolerated under the reaction conditions. Georg Thieme Verlag Stuttgart.

SYNTHESIS AND MASS SPECTRAL STUDIES OF FLUORINE CONTAINING 5a, 7b, 12a, 14b-TETRAHYDROBISINDOLO BENZO DIFURANS

2:1 Cycloadducts (-H2) are formed when various fluorinated 2-arylindoles are stirred with p-benzoquinone in acidic medium and are identified as dimers of the type 5a, 7b, 12a, 14b-tetrahydrobisindolo benzo difurans.All the synthesized compounds have been characterized by their analytical and spectral (IR, PMR, 19F NMR and Mass) data.