7007-16-1Relevant academic research and scientific papers
Synthesis of Chiral Selenazolines from N-Acyloxazolidinones via a Selenative Rearrangement of Chiral Cyclic Skeletons
Shibahara, Fumitoshi,Fukunaga, Tomoki,Kubota, Saki,Yoshida, Akihito,Murai, Toshiaki
supporting information, p. 5826 - 5830 (2018/09/25)
A synthetic route to chiral selenazolines from readily available N-acyloxazolidinones via a selenative rearrangement of a chiral cyclic skeleton is reported. The reaction proceeds in the presence of elemental selenium, a hydrochlorosilane, and an amine. A
Decarboxylative isomerization of N-Acyl-2-oxazolidinones to 2-oxazolines
May, Aaron E.,Willoughby, Patrick H.,Hoye, Thomas R.
, p. 3292 - 3294 (2008/09/20)
(Chemical Equation Presented) N-Acyl-2-oxazolidinones are ring-opened by lithium iodide and decarboxylated in the presence of a mild proton source. Further reaction with an amine base provides 2-oxazolines. The transformation is general for oxazolidinones unsubstituted in the 5 position and occurs under mild conditions (25-50°C). These results complement the existing methods for this transformation by allowing lower temperatures and/or avoiding metal catalysts.
A facile one-pot solid-phase synthesis of oxazolidin-2-ones using polymer-supported 2-hydroxyalkyl selenide reagent
Hu, Qiao-Sheng,Sheng, Shou-Ri,Lin, Shu-Ying,Wei, Mei-Hong,Xin, Qin,Liu, Xiao-Ling
, p. 74 - 75 (2008/02/04)
A simple, efficient and environmentally friendly procedure for one-pot solid-phase synthesis of 2-oxazolidinones in moderate to good yields by reaction of polystyrene-supported 2-hydroxyalkyl selenide with benzoyl isocyanate and subsequent oxidation/cycli
Cycloaddition Reaction of Heterocumulenes with Oxiranes Catalyzed by an Organotin Iodide-Lewis Base Complex
Shibata, Ikuya,Baba, Akio,Iwasaki, Hiroyuki,Matsuda, Haruo
, p. 2177 - 2184 (2007/10/02)
Organotin halide-Lewis base complexes are versatile catalysts for the cycloaddition of heterocumulenes with oxiranes and afford good yields of five-membered heterocyclic compounds under mild and neutral conditions.The catalysts are sufficiently active tha
