700804-17-7

Upstream product

• 20327-23-5 1-cyclopropylpiperazine 
• 350-46-9 4-Fluoronitrobenzene 
• 700804-16-6 1-cyclopropyl-4-(4-nitrophenyl)piperazine 

Downstream Products

• 1403819-01-1 N-(4-(4-cyclopropylpiperazin-1-yl)phenyl)-5-(2,6-difluorophenyl)-1H-pyrazolo[4,3-d]pyrimidin-7-amine 
• 1403818-97-2 N-(4-(4-cyclopropylpiperazin-1-yl)phenyl)-5-(2-fluorophenyl)-1H-pyrazolo[4,3-d]pyrimidin-7-amine 
• 1403817-22-0 N-(4-(4-cyclopropylpiperazin-1-yl)phenyl)-5-(2,5-dimethoxyphenyl)-1H-pyrazolo[4,3-d]pyrimidin-7-amine 
• 1403819-11-3 N-(4-(4-cyclopropylpiperazin-1-yl)phenyl)-5-(thiophen-2-yl)-1H-pyrazolo[4,3-d]pyrimidin-7-amine 
• 1403886-71-4 [4-(4-cyclopropyl-piperazin-1-yl)-phenyl]-(8-methoxy-2H-pyrazolo[3,4-c]quinolin-4-yl)-amine 

Relevant academic research and scientific papers

PHENYLAMINOPYRIMIDINE AMIDE AUTOPHAGY INHIBITORS AND METHODS OF USE THEREOF

Described herein are compounds that are inhibitors of autophagy and their use in the treatment of disorders such as cancers.

HETEROCYCLIC COMPOUNDS AND USES THEREOF

Heterocyclic compounds as Wee1 inhibitors are provided. The compounds may find use as therapeutic agents for the treatment of diseases and may find particular use in oncology.

PYRIMIDOPYRIMIDINONES USEFUL AS WEE-1 KINASE INHIBITORS

The present invention relates to compounds that are useful as inhibitors of the activity of Wee-1 kinase. The present invention also relates to pharmaceutical compositions comprising these compounds and to methods of using these compounds in the treatment of cancer and methods of treating cancer.

TRIAZOLOPYRIDINE COMPOUNDS USEFUL FOR THE TREATMENT OF DEGENERATIVE and INFLAMMATORY DISEASES

Novel triazolopyridine compounds are disclosed that have a formula represented by Formula (I). The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non- limiting example, ECM degradation, joint degradation and/or inflammation, and others.