700868-16-2Relevant academic research and scientific papers
The Aza Diels-Alder Reaction on Brominated Conjugated Dienes
Navarro, Jorge A. R.,Oltra, J. Enrique,Roldan-Molina, Esther,Uceda, Rafael G.
, p. 2003 - 2005 (2021)
The use of electron-deficient dienes as substrates in the aza Diels-Alder reaction (ADA) has been studied scarcely. However, the ADA process offers a wide range of applications in organic synthesis. In this communication, the reaction between different brominated conjugated dienes and 4-phenyl-1,2,4-triazoline-3,5-dione (PTAD), one of the most vigorous dienophiles, is reported. We have synthesized tricyclic compounds from acyclic substrates in only two steps, considering variables such as ring size and steric hindrance and substantially improved the results obtained with other dienophiles.
CpTiCl2-Catalyzed Cross-Coupling between Internal Alkynes and Ketones: A Novel Concept in the Synthesis of Halogenated, Conjugated Dienes
Roldan-Molina, Esther,Nievas, Maria M.,Navarro, Jorge A. R.,Oltra, J. Enrique
supporting information, p. 8296 - 8301 (2020/06/17)
A novel concept for the synthesis of halogenated, conjugated dienes is disclosed: the CpTiCl2-catalyzed coupling of keto-alkynes, in the presence of Me3SiBr/Et3N?HBr. This reaction provided five-, six-, and seven-membered
Ti-catalyzed straightforward synthesis of exocyclic allenes
Munoz-Bascon, Juan,Hernandez-Cervantes, Carmen,Padial, Natalia M.,Alvarez-Corral, Miriam,Rosales, Antonio,Rodriguez-Garcia, Ignacio,Oltra, J. Enrique
supporting information, p. 801 - 810 (2014/01/23)
Exocyclic allenes constitute useful building blocks in organic synthesis and have recently been identified as key intermediates in the synthesis of natural products. Here the first general method for the most straightforward synthesis of exocyclic allenes
