70097-13-1

Usage

Uses

Used in Pharmaceutical Industry:
2-(4-NITRO-PHENYL)-QUINOLINE-4-CARBOXYLIC ACID is used as a building block for the synthesis of various pharmaceutical compounds. Its unique structure allows for the development of new drugs with potential therapeutic benefits.
Used in Medicinal Applications:
2-(4-NITRO-PHENYL)-QUINOLINE-4-CARBOXYLIC ACID is being studied for its anti-inflammatory and antibacterial activities. Its potential medicinal properties make it a promising candidate for the treatment of various inflammatory and infectious diseases.
Used in Biochemical and Cell Biological Research:
2-(4-NITRO-PHENYL)-QUINOLINE-4-CARBOXYLIC ACID is used as a fluorescent probe in biochemical and cell biological studies. Its distinctive properties enable researchers to investigate cellular processes and mechanisms, contributing to a better understanding of biological systems.

InChI:InChI=1/C16H10N2O4/c19-16(20)13-9-15(17-14-4-2-1-3-12(13)14)10-5-7-11(8-6-10)18(21)22/h1-9H,(H,19,20)

Upstream product

• 95201-24-4 ethyl 2-(4'-nitrophenyl)-quinoline-4-carboxylate 
• 91-56-5 indole-2,3-dione 
• 100-19-6 (4-nitrophenyl)ethanone 
• 5467-57-2 2-chloroquinoline-4-carboxylic acid 
• 132-60-5 cinchophen 
• 127-17-3 2-oxo-propionic acid 
• 785-80-8 p-nitrobenzylideneaniline 
• 56680-34-3 3-(4'-nitrobenzoyl)-methyleneindol-2-one 
• 70097-11-9 3-hydroxy-3-(2-oxo-2-(4-nitrophenyl)ethyl)indolin-2-one 
• 555-16-8 4-nitrobenzaldehdye 
• 62-53-3 aniline 

Downstream Products

• 132-60-5 cinchophen 

Relevant academic research and scientific papers

Energy efficient Pfitzinger reaction: A novel strategy using a surfactant catalyst

A novel energy efficient method for the Pfitzinger reaction is demonstrated, which is catalysed using a surfactant, cetyltrimethylammonium hydroxide. The surfactant nature of the catalyst caused the substrate to be soluble in aqueous media, which enhanced the interaction of the catalyst with the substrate. An increase in the rate of reaction and more than 78% of energy saving were observed under ultrasonic irradiation.

STAT3 INHIBITOR CONTAINING QUINOLINECARBOXAMIDE DERIVATIVE AS ACTIVE INGREDIENT

The present invention provides a STAT3 inhibitor containing as an active ingredient, a quinolinecarboxamide derivative represented by the formula (I) (in the formula, W represents a bond or an alkylene chain; X represents O, S, or NR34; and Rs

One-pot synthesis of quinoline-4-carboxylic acid derivatives in water: Ytterbium perfluorooctanoate catalyzed Doebner reaction

Ytterbium perfluorooctanoate [Yb(PFO)3] has been proved to be an efficient catalyst for Doebner reaction of pyruvic acid, aldehydes and amines under mild conditions in water to afford quinoline-4-caboxylic acid derivatives with three component one-pot method in good yields. The process is operationally simple and environmentally benign and the catalyst has readily been recycled for several times with consistent activity. Furthermore, a plausible mechanism for this transformation is also presented.

Separation of 2(3),9(10),16(17),23(24)-tetrasubstituted phthalocyanines with newly developed HPLC phases

The synthesis of 2(3),9(10),16(17),23(24)-tetrasubstituted phthalocyanines from 1,2-dicyano-4-alkoxybenzenes or the corresponding isoindolines is reported. In each case, four isomers with D(2h), C(4h), C(2v), and C(s) symmetry are obtained in the statisti