701-69-9Relevant articles and documents
Chemo- and product-selective electrooxidation of 3-(arylthiomethyl)- Δ3-cephems
Tanaka, Hideo,Tokumaru, Yoshihisa,Fukui, Ken-Ichi,Kuroboshi, Manabu,Torii, Sigeru,Jutand, Anny,Amatore, Christian
experimental part, p. 3449 - 3459 (2010/02/28)
Electrolysis of 3-arylthiomethyl-Δ3-cephems possessing various substituents on the arylthio moiety undergo chemo selective and product-selective electrooxidation to give several different products. These include isomeric mixtures of the corresponding methoxylated cephems, a bis[(Δ3-cephem-3-yl)methyl]disulfide or a 3-dimethoxymethyl- Δ3-cephem. The selectivity of the oxidation is highly dependent on the nature of the substituents on the arylthio moiety which suggests that both steric and electronic effects play an important role in the electrooxidation of 3-arylthiomethyl-Δ3-cephems.
SPIROCYCLIC SULFONAMIDES AND RELATED COMPOUNDS
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Page/Page column 57, (2010/11/29)
Spirocyclic sulfonamides and related compounds of Formula 1 are provided : (Formula (I)): in which the variables are as described herein. Such compounds may be used to modulate bradykinin receptor activity in vivo or in vitro, and are particularly useful