70112-91-3Relevant articles and documents
Binuclear isophthaloylbis(N,N-diphenylthioureate) transition metal complexes: Synthesis, spectroscopic, thermal and structural characterization
Teixeira, Estefane Isis,Schwalm, Cristiane Storck,Casagrande, Gleison Ant?nio,Tirloni, Bárbara,Schwade, Vania Denise
, (2020)
The isophthaloylbis(N,N-diphenylthiourea) molecule (H2L ligand) reacts with CuI, CuII, MnIII, FeII, FeIII and CoII ions to form binuclear complexes with formula [M2(L-
Bis-Thiourea bearing aryl and amino acids side chains and their antibacterial activities
Wan Zullkiplee, Wan Sharifatun Handayani,Abd Halim, Ainaa Nadiah,Ngaini, Zainab,Mohd Ariff, Maya Asyikin,Hussain, Hasnain
, p. 832 - 838 (2014/07/08)
(Equation present) A series of symmetrical 1,3-bis thiourea 1a-e and 1,4-bis thiourea derivatives 2a-e have been successfully synthesized from the reactions of amines with 3-acetylbenzoyl isothiocyanate and 4-acetylbenzoyl isothiocyanate, respectively. All the synthesized compounds were characterized by FT-IR spectroscopy and 1H and 13C NMR spectroscopy. The compounds were screened for their antibacterial activity by turbidimetric method using gram-negative bacteria (E. coli ATCC 8739) using turbidimetric method. The newly synthesized bis-thiourea derivatives bearing aryl side chains showed good antibacterial activity against E. coli. The effect of the molecular structure of the synthesized compounds on the antibacterial activity is discussed. 2014 Copyright Taylor & Francis Group, LLC.
Synthesis, characterization and antibacterial activity of some novel symmetrical N3, N3'-Bis(disubstituted)isophthalyl- bis(thioureas) and their Cu(II) and Ni(II) complexes
Jamil, Muhammad,Zubair, Muhammad,Farid, Muhammad Asim,Altaf, Ataf Ali,Rasool, Nasir,Bukhari, Iftikhar Hussain,Rizwan, Komal,Ahmad, Viqar Uddin
, p. 834 - 839 (2013/07/26)
A series of some novel N3,N3'-bis(disubstituted) isophthalyl-bis(thioureas) compounds with general formula [C6H 4{CONHCSNHR}2], where R = 4-C6H 4COOH(L1), 3-NO2C6H 4(L2), 2- NO2C6H4(L 3), 4-CH3C6H4(L4), 2-CH3C6H4(L5), 3-CH 3C6H4(L6) and their Cu(II) and Ni(II) complexes have been synthesized. (L1-L6) have been prepared in good to excellent yields by reaction of isophthaloyl isothiocyanate with primary amines using dry acetone as solvent. The stoichiometric reaction between the metal (II) ion and synthesized ligands in molar ratio of M : L (1 : 1) resulted in the formation of the metal complexes of type [ML]2 (where M = Cu(II) and Ni(II). These compounds (L1-L6) and their metal (II) complexes have been characterized by elemental analyses, Infrared spectroscopy, 1H-NMR spectroscopy, magnetic moments, and electronic spectral measurements. These compounds (L1-L6) and their metal (II) complexes were also screened for their antibacterial activity against bacterial species, Bacillus subtilis, Staphylococcus aureus, Escherichia coli, Shigella sonnei, Salmonella typhi and Pseudomonas aeroginosa. Some compounds showed potential activity against a number of bacterial strains. The results of these studies also show the metal (II) complexes to be having stronger antibacterial activityl against one or more species as compared to the uncomplexed ligands. It was concluded that these compounds may be the potential source of active antibacterial agents.