70132-87-5 Usage
Uses
Used in Pharmaceutical Industry:
CHEMBRDG-BB 6619297 is used as a kinase inhibitor for targeting specific enzymes involved in cell signaling and regulation. Its ability to block these enzymes makes it a promising candidate for the development of therapeutic agents to treat cancer, inflammatory diseases, and other conditions related to abnormal cell proliferation and signaling.
Used in Cancer Treatment:
CHEMBRDG-BB 6619297 is used as an anticancer agent for inhibiting the activity of kinases that are often dysregulated in cancer cells. By blocking these enzymes, it can potentially suppress tumor growth, prevent metastasis, and enhance the effectiveness of conventional cancer therapies.
Used in Inflammatory Disease Management:
CHEMBRDG-BB 6619297 is used as an anti-inflammatory agent for modulating the activity of kinases involved in inflammatory responses. Its ability to inhibit these enzymes can help reduce inflammation, alleviate pain, and improve the overall quality of life for patients suffering from inflammatory diseases.
Used in Drug Discovery and Development:
CHEMBRDG-BB 6619297 serves as a valuable compound in drug discovery and development efforts. Its kinase inhibitory properties make it a useful tool for researchers to study the role of kinases in various diseases and to develop novel therapeutic agents targeting these enzymes.
Used in Research and Development of Targeted Therapies:
CHEMBRDG-BB 6619297 is used as a research tool for the development of targeted therapies. Its ability to selectively inhibit specific kinases can help researchers identify potential therapeutic targets and design drugs that specifically target these enzymes, leading to more effective and less toxic treatments for various diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 70132-87-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,0,1,3 and 2 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 70132-87:
(7*7)+(6*0)+(5*1)+(4*3)+(3*2)+(2*8)+(1*7)=95
95 % 10 = 5
So 70132-87-5 is a valid CAS Registry Number.
InChI:InChI=1/C14H10ClNO4/c1-20-11-5-2-9(3-6-11)14(17)12-8-10(16(18)19)4-7-13(12)15/h2-8H,1H3
70132-87-5Relevant academic research and scientific papers
PROCESS FOR THE PREPARATION OF 6-(PERFLUOROALKYL)URACIL COMPOUNDS FROM CARBAMATE COMPOUNDS
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Page 19, (2010/02/06)
An improved process for the preparation of 6-(perfluoroalkyl)uracil compounds having structural formula (I) from carbamate compounds having structural formula (II).
Synthesis and antitumor activity of novel benzophenone derivatives
Kumazawa, Eiji,Hirotani, Kenji,Burford, S. Clifford,Kawagoe, Keiichi,Miwa, Tamotsu,Mitsui, Ikuo,Ejima, Akio
, p. 1470 - 1474 (2007/10/03)
Novel benzophenone derivatives were synthesized and screened for cytotoxic and antitumor activity. Friedel-Crafts condensation was employed to construct the benzophenone skeleton. Among the compounds synthesized, morpholino and thiomorpholino benzophenones 3a-d exhibited potent cytotoxic activity against P388 murine leukemia and PC-6 human lung carcinoma cells in vitro, and compounds 3a, 3c, and 3j, when administered intraperitoneally, showed significant antitumor activity against the malignant ascites caused by intraperitoneal inoculation of P388 cells in mice.
(Benzoylphenyl)piperidines: A new class of immunomodulators
Bellamy,Chazan,Dodey,Dutartre,Ou,Pascal,Robin
, p. 1545 - 1552 (2007/10/02)
A series of (benzoylphenyl)piperidines has been synthesized and evaluated for activity as immunomodulators. Several of these compounds show good activity in primary screening on the basis of the lymphocytes mitogenic response to Con A, PHA, and PWM. A chloro group in position 4 of the benzoyl moiety as well as an amino group (or a carbamate derivative) para to the piperidine nucleus seems to be essential for activity. The depicted compounds may be considered as the first examples of a new series of immunomodulators.
