70165-35-4Relevant academic research and scientific papers
Copper-catalyzed redox-neutral C-H amination with amidoximes
Chen, Hui,Chiba, Shunsuke
, p. 42 - 46 (2014/01/06)
CuI-catalyzed reactions of N-alkylamidoximes afforded dihydroimidazoles via sp3 C-H amination. On the other hand, the reactions of N-benzoylamidoximes resulted in sp2 C-H amination to form quinazolinones. The reaction mechanisms could be characterized as a redox-neutral radical pathway including a Cu(i)-Cu(ii) redox catalytic cycle. The Royal Society of Chemistry.
Copper-catalyzed aliphatic C-H amination with an amidine moiety
Chen, Hui,Sanjaya, Stephen,Wang, Yi-Feng,Chiba, Shunsuke
, p. 212 - 215 (2013/04/23)
A method for amination of aliphatic C-H bonds of N-alkylamidines is described that utilizes Cu(OAc)2 as the catalyst in the presence of PhI(OAc)2 and K3PO4. The resulting products, dihydroimidazoles and tetrahydropyrimidines, could be converted into the corresponding diamines by hydride reduction.
