70170-23-9

Basic information

• Product Name: 5-METHYL-2-PHENYL-1,3-OXAZOLE-4-CARBALDEHYDE
• Synonyms: 5-METHYL-2-PHENYL-1,3-OXAZOLE-4-CARBOXALDEHYDE;5-METHYL-2-PHENYL-1,3-OXAZOLE-4-CARBALDEHYDE;5-Methyl-2-phenyl-1,3-oxazole-4-carboxaldehyde 97%;4-Formyl-5-methyl-2-phenyl-1,3-oxazole, (4-Formyl-5-methyl-1,3-oxazol-2-yl)benzene;5-methyl-2-phenyloxazole-4-carbaldehyde
• CAS NO: 70170-23-9
• Molecular Formula: C₁₁H₉NO₂
• Molecular Weight: 187.19
• Mol File: 70170-23-9.mol
• Article Data: 5

Chemical Properties

• Melting Point: 87 °C
• Boiling Point: 341.173°C at 760 mmHg
• Flash Point: 160.136°C
• Appearance: /
• Density: 1.18g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.58
• CAS DataBase Reference: 5-METHYL-2-PHENYL-1,3-OXAZOLE-4-CARBALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-METHYL-2-PHENYL-1,3-OXAZOLE-4-CARBALDEHYDE(70170-23-9)
• EPA Substance Registry System: 5-METHYL-2-PHENYL-1,3-OXAZOLE-4-CARBALDEHYDE(70170-23-9)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36
• Safety Statements: 26
• Hazardous Substances Data: 70170-23-9(Hazardous Substances Data)

Usage

General Description

5-METHYL-2-PHENYL-1,3-OXAZOLE-4-CARBALDEHYDE is a chemical compound that belongs to the oxazole family and is characterized by a five-membered ring containing one oxygen and one nitrogen atom. It is a yellowish liquid with a high boiling point and is commonly used as an intermediate in the synthesis of various pharmaceuticals, agrochemicals, and natural products. Its unique structure and reactivity make it useful in the production of many different compounds. Additionally, it has been found to exhibit antimicrobial and antioxidant properties, making it of interest for potential therapeutic applications. However, it is important to handle this compound with caution, as it can be volatile and toxic when exposed to high temperatures or inhaled.

InChI:InChI=1/C11H9NO2/c1-8-10(7-13)12-11(14-8)9-5-3-2-4-6-9/h2-7H,1H3

Upstream product

• 51655-71-1 2-phenyl-5-methyl-4-oxazolecarboxylic acid chloride 
• 100-52-7 benzaldehyde 
• 27492-46-2 4,5-dimethyl-2-phenyl-oxazole 3-oxide 
• 103788-61-0 (5-methyl-2-phenyl-4-oxazolyl)methyl chloride 
• 18735-74-5 5-methyl-2-phenyloxazole-4-carboxylic acid 
• 61151-96-0 ethyl 5-methyl-2-phenyloxazole-4-carboxylate 
• 70502-03-3 [5-methyl-2-phenyl-1,3-oxazol-4-yl]methanol 

Downstream Products

• 141200-22-8 5-{4-[(E)-3-(5-Methyl-2-phenyl-oxazol-4-yl)-acryloyl]-benzyl}-thiazolidine-2,4-dione 
• 132451-15-1 N-methyl-N-<(5-methyl-2-phenyl-4-oxazolyl)methyl>-4<(2,4-dioxothiazolidin-5-yl)methyl>benzenesulfonamide 
• 132451-19-5 N-methyl-N-<(5-methyl-2-phenyl-4-oxazolyl)methyl>-4<(2,4-dioxothiazolidin-5-yl)methyl>benzamide 
• 132451-17-3 N-methyl-N-<(5-methyl-2-phenyl-4-oxazolyl)methyl>-4<(2,4-dioxothiazolidin-5-ylidene)methyl>benzamide 
• 132451-31-1 4-methylaminocarbonyl>benzaldehyde 
• 132451-29-7 N-methyl-N-[(5-methyl-2-phenyl-4-oxazolyl)-methyl]amine 

Relevant articles and documents

1,3-Oxazole-isoniazid hybrids: Synthesis, antitubercular activity, and their docking studies

A series of novel N′-([2-aryl-5-methyl-1,3-oxazole-4-yl]methylene)isonicotino/nicotino hydrazides 10a-l were prepared by the condensation reaction of 2-aryl-5-methyl-1,3-oxazole-4-carbaldehydes 8a-f with the corresponding isonicotino/nicotino hydrazides 9

Thiazolidinedione derivatives as hypoglycemic agents

Hypoglycemic thiazolidine-2,4-dione derivatives of the formula STR1 wherein the dotted line represents a bond or no bond; V is --CH=CH--, --N=CH--, --CH=N--, S, O or NR; W is S, SO, SO2, SO2 NR1, NR1 SO2/s

Thiazolidinedione derivatives as hypoglycemic agents

Hypoglycemic thiazolidine-2,4-dione derivatives of the formula wherein the dotted line represents a bond or no bond;, V is -CH=CH-, -N=CH-, -CH=N-, S, O or NR;, W is S, SO, SO2, SO2NR1, NR1SO2, CONR1 or NR1CO;, X is S, O,