701913-55-5Relevant academic research and scientific papers
Dual enzyme-responsive "turn-on" fluorescence sensing systems based on in situ formation of 7-hydroxy-2-iminocoumarin scaffolds
Debieu, Sylvain,Romieu, Anthony
, p. 10348 - 10361 (2015/10/28)
A new strategy for the simultaneous fluorogenic detection of two distinct enzyme activities namely hydrolase (amidase or esterase) and reductase is described. This innovative biosensing method is based on the powerful "covalent-assembly" principle that in
Reagents and assay strategies for quantifying active enzyme analytes using a personal glucose meter
Mohapatra, Hemakesh,Phillips, Scott T.
supporting information, p. 6134 - 6136 (2013/07/26)
This communication describes small molecule reagents and a rapid single-step assay for quantifying nanomolar levels of active enzyme analytes using a personal glucose meter. The Royal Society of Chemistry 2013.
Bioactivation of carbamate-based 20(S)-camptothecin prodrugs
Pessah, Neta,Reznik, Mika,Shamis, Marina,Yantiri, Ferda,Xin, Hong,Bowdish, Katherine,Shomron, Noam,Ast, Gil,Shabat, Doron
, p. 1859 - 1866 (2007/10/03)
Two new prodrugs of CPT were synthesized, based on carbamate linkages between the 20-hydroxy group of CPT and a linker designed to be enzymatically removed by either Penicillin-G-Amidase or catalytic antibody 38C2. Cell growth inhibition assays showed an
