70242-69-2Relevant articles and documents
Steroidal derived acids as inhibitors of human Cdc25A protein phosphatase
Peng, Hairuo,Xie, Wenge,Kim, Deog-Il,Zalkow, Leon H.,Powis, Garth,Otterness, Diane M.,Abraham, Robert T.
, p. 299 - 306 (2007/10/03)
A group of steroidal derived acids were synthesized and found to be human Cdc25A inhibitors. Their potency ranged from 1.1 to > 100 μM; the best ones compare very favorably with that of the novel cyano-containing 5,6-seco- cholesteryl acid 1 (IC50/s