702675-42-1 Usage
General Description
N-(3-(5-Bromo-4-(3-(thiophene-2-carboxamido)propylamino)pyrimidin-2-ylamino)phenyl)pyrrolidine-1-carboxamide is a chemical compound with a complex molecular structure. It contains a pyrrolidine-1-carboxamide group linked to a phenyl group and a pyrimidin-2-ylamino group. Additionally, it features a thiophene-2-carboxamido group attached to a propylamino group. The compound also includes a bromine atom at the 5-position of the phenyl group. This chemical may have potential applications in various fields such as pharmaceuticals, agrochemicals, or materials science, but further research would be necessary to determine its specific uses and properties.
Check Digit Verification of cas no
The CAS Registry Mumber 702675-42-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,0,2,6,7 and 5 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 702675-42:
(8*7)+(7*0)+(6*2)+(5*6)+(4*7)+(3*5)+(2*4)+(1*2)=151
151 % 10 = 1
So 702675-42-1 is a valid CAS Registry Number.
InChI:InChI=1/C23H26BrN7O2S/c24-18-15-27-22(30-20(18)25-9-5-10-26-21(32)19-8-4-13-34-19)28-16-6-3-7-17(14-16)29-23(33)31-11-1-2-12-31/h3-4,6-8,13-15H,1-2,5,9-12H2,(H,26,32)(H,29,33)(H2,25,27,28,30)
702675-42-1Relevant articles and documents
Synthesis and structure-activity relationships of a novel series of pyrimidines as potent inhibitors of TBK1/IKKε kinases
McIver, Edward G.,Bryans, Justin,Birchall, Kristian,Chugh, Jasveen,Drake, Thomas,Lewis, Stephen J.,Osborne, Joanne,Smiljanic-Hurley, Ela,Tsang, William,Kamal, Ahmad,Levy, Alison,Newman, Michelle,Taylor, Debra,Arthur, J. Simon C.,Clark, Kristopher,Cohen, Philip
, p. 7169 - 7173,5 (2012/12/12)
The design, synthesis and structure-activity relationships of a novel series of 2,4-diamino-5-cyclopropyl pyrimidines is described. Starting from BX795, originally reported to be a potent inhibitor of PDK1, we have developed compounds with improved selectivity and drug-like properties. These compounds have been evaluated in a range of cellular and in vivo assays, enabling us to probe the putative role of the TBK1/IKKε pathway in inflammatory diseases.
