702702-62-3Relevant academic research and scientific papers
Room-Temperature Palladium(II)-Catalyzed Direct 2-Arylation of Indoles with Tetraarylstannanes
Liu, Yuxia,Wang, Chao,Huang, Linjuan,Xue, Dong
, p. 1613 - 1618 (2020/09/15)
A palladium(II)-catalyzed direct 2-arylation of indoles by tetraarylstannanes with oxygen (balloon) as the oxidant at room temperature has been developed. Various tetraarylstannanes can be employed as aryl sources for 2-arylation of indoles in up to 89% yield, providing a practical and efficient catalytic protocol for accessing 2-arylindoles.
Selective cyclization of alkynols and alkynylamines catalyzed by potassium tert-butoxide
Li, Deng Yuan,Shi, Ke Ji,Mao, Xiao Feng,Le Zhao, Zheng,Wu, Xin Yan,Liu, Pei Nian
, p. 7022 - 7031 (2015/03/14)
Potassium tert-butoxide (t-BuOK) was found to be an effective catalyst for the cyclization of aromatic alkynols and alkynylamines. In the presence of 10 mol % t-BuOK, a range of alkynols were converted to the corresponding exo-cyclic enol ethers as pure Z
Pd(OAc)2-catalyzed regioselective arylation of indoles with arylsiloxane in acidic medium
Liang, Zunjun,Yao, Bangben,Zhang, Yuhong
supporting information; scheme or table, p. 3185 - 3187 (2010/08/20)
(Figure Presented) Mild conditions have been developed to achieve a Pd(OAc)2-catalyzed cross-coupling between indoles and arylsiloxanes in the presence of TBAF and Ag2O in acidic medium. Electron-deficient arylsiloxanes presented high efficiency in this system to give the arylated indoles in excellent yields.
N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS
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Page 45, (2010/02/07)
The present invention describes substituted 3-Aminoalkoxyindoles, as compounds of the general formula (I), its stereoisomers, its radioisotopes, its geometric forms, its N-oxides, its polymorphs, its pharmaceutically acceptable salts, its pharmaceutically acceptable solvates, its useful bioactive metabolites and any suitable combination of the above. The invention also discloses the processes for preparing such compounds of the general formula (I), its stereoisomers, its radioisotopes, its geometric forms, its N-oxides, its polymorphs, its pharmaceutically acceptable salts, its pharmaceutically acceptable solvates, its useful bio-active metabolites and also includes any suitable combination of the above. Further described are various methods of administering these compounds of general formula (I), i.e. pharmaceutically acceptable dosage forms, their composition and their use in either therapy or diagnosis.
