7029-89-2

Usage

Chemical compound

2,3-diphenylbenzo[g]quinoxaline-5,10-dione

Class

Quinoxaline derivatives

Structure

Cyclic compound with two phenyl groups and a benzo[g]quinoxaline ring with a 5,10-dione functional group

Applications

Potential applications in organic chemistry, medicinal chemistry, and drug development

Value

Valuable building block for the synthesis of various organic compounds and pharmaceuticals

Biological activity

May exhibit biological activity and could be of interest in the study of potential pharmacological effects

Research

Further research and exploration of properties needed to fully understand potential uses and applications

Upstream product

• 13755-95-8 2,3-diamino-1,4-naphthoquinone 
• 134-81-6 benzil 
• 36305-72-3 2,3-diphenylbenzoquinoxaline 
• 771-97-1 2,3-Diaminonaphthalene 
• 92-44-4 2,3-naphthalenediol 
• 2050-75-1 2,3-dichloronaphthalene 
• 13755-95-8 2,3-Diamino-1,4-naphthohydrochinon 
• 100-52-7 benzaldehyde 

Downstream Products

• 107041-55-4 2-(10-Dicyanomethylene-2,3-diphenyl-10H-benzo[g]quinoxalin-5-ylidene)-malononitrile 
• 108059-27-4 (2S,3R)-2,3-Diphenyl-1,2,3,4-tetrahydro-benzo[g]quinoxaline-5,10-dione 
• 108059-30-9 cis-1-Acetyl-1,2,3,4-tetrahydro-2,3-diphenylbenzochinoxalin-5,10-chinon 

Relevant academic research and scientific papers

Synthesis of benzo[g]quinoxaline-5,10-dione based pyridine derivatives and their antimycobacterial activity

Thirteen new compounds belonging to series 2-amino-6-(5,10-dioxo-2,3-diphenyl-5,10-dihydrobenzo[g]quinoxalin-7-yl)-4-(substituted)phenylpyridine-3-carbonitrile (6a-m) were synthesized by multistep synthetic scheme. The newly synthesized compounds were screened for their antimycobacterial activity by L.J. Slope (Conventional) Method. Compound 6h with 4-N(CH3)2 group at phenyl ring of above mentioned position has been reported as most active antimycobacterial compound and compound 6k with 4-CH3 substitution at phenyl above mentioned position has been reported as the least active antimycobacterial compound.

Synthesis and in vitro antimycobacterial activity of 7-[3-(substituted) phenylprop-2-enoyl]-2,3-diphenyl- 5H,10H-benzo[g]quinoxaline-5,10-diones

Eleven new compounds diones namely, 7-[3-(substituted) phenylprop-2-enoyl]-2,3-diphenyl- 5H,10H-benzo[g]quinoxaline-5,10-dione (6a-k) were synthesized by multistep synthetic scheme. The newly synthesized compounds were submitted for their in vitro antimycobacterial activity against Mycobacterium tuberculosis H37Rv by L.J. Slope (Conventional) Method. Compound 6e having 4-OCH3 at phenyl ring attached to 3-position of prop-2-enoyl group has been observed as the most active antimycobacterial compound, while compound 6h having 4-CF3 group on the above-mentioned position has been observed as the least active antimycobacterial compound of the newly synthesized series.

Synthesis and Structure Analysis of 1,2,3,4-Tetrahydrobenzoquinoxaline-5,10-quinones

2,3-Diamino-1,4-dihydroxynaphthalene reacts with different aromatic aldehydes to give 2,3-disubstituted 1,2,3,4-tetrahydrobenzoquinoxaline-5,10-quinones (1-7).In the course of the reaction a new C-C bond is formed stereoselectively.The yields are in th