703-33-3

Usage

Uses

Used in Research Applications:
5,8-Dichloropyrido[2,3-d]pyridazine is used as a research chemical for the study of its properties and potential applications. Due to the limited information available about its physical properties, safety, and medicinal properties, it is primarily used in controlled research environments to explore its characteristics and possible uses.
Used in Chemical Synthesis:
5,8-Dichloropyrido[2,3-d]pyridazine is used as a chemical intermediate in the synthesis of other compounds. Its unique structure and reactivity make it a valuable building block for the development of new chemical entities, particularly in the field of organic chemistry.
Used in Pharmaceutical Research:
Although there is scarce information about its medicinal properties, 5,8-dichloropyrido[2,3-d]pyridazine is used as a potential candidate in pharmaceutical research. Its structure may offer opportunities for the development of new drugs or drug-like molecules, and further investigation is needed to understand its potential therapeutic applications.
Used in Industrial Applications:
While there is limited information about the industrial applications of 5,8-dichloropyrido[2,3-d]pyridazine, its unique chemical properties may make it a valuable component in the development of new materials or processes. Further research and development are required to explore its potential uses in various industries.

InChI:InChI=1/C7H3Cl2N3/c8-6-4-2-1-3-10-5(4)7(9)12-11-6/h1-3H

Upstream product

• 4430-77-7 pyrido[2,3-d]pyridazine-5,8(6H,7H)dione 
• 699-98-9 Pyridine-2,3-dicarboxylic anhydride 
• 4430-77-7 6,7-dihydropyrido[2,3-d]pyridazine-5,8-dione 

Downstream Products

• 2942-32-7 6-Chloro-1,2,4-triazolo<4,3-b>pyrido<2,3-d>pyridazine 
• 23590-60-5 8-chloro-6H-pyrido[2,3-d]pyridazin-5-one 
• 23590-61-6 5-chloro-7H-pyrido[2,3-d]pyridazin-8-one 
• 81214-63-3 8-aminopyrido<2,3-d>pyridazine-5(6H)-one 
• 81214-61-1 5-chloro-7-acetylpyrido<2,3-d>pyridazine-8(7H)-one 
• 1133750-26-1 (R)-(4-(8-chloropyrido[3,2-d]pyridazin-5-yl)-3-methylpiperazin-1-yl)(phenyl)methanone 
• 1133750-24-9 (R)-(4-(5-chloropyrido[2,3-d]pyridazin-8-yl)-3-methylpiperazin-1-yl)(phenyl)methanone 
• 1365803-37-7 8-chloro-N-(3-(trifluoromethyl)phenyl)pyrido[2,3-d]pyridazin-5-amine 
• 1365803-36-6 5-chloro-N-(3-(trifluoromethyl)phenyl)pyrido[3,2-d]pyridazin-8-amine 
• 1365802-43-2 methyl 4-(5-{[3-(trifluoromethyl)phenyl]amino}pyrido[2,3-d]pyridazin-8-yl)benzoate 

Relevant academic research and scientific papers

KRAS G12C INHIBITORS AND METHODS OF USING THE SAME

Provided herein are KRAS G12C inhibitors, composition of the same, and methods of using the same. These inhibitors are useful for treating a number of disorders, including pancreatic, colorectal, and lung cancers.

KRAS G12C INHIBITORS AND METHODS OF USING THE SAME

Provided herein are KRAS G12C inhibitors, composition of the same, and methods of using the same. These inhibitors are useful for treating a number of disorders, including pancreatic, colorectal, and lung cancers.

KRAS G12C INHIBITORS AND METHODS OF USING THE SAME

Provided herein are KRAS G12C inhibitors, composition of the same, and methods of using the same. These inhibitors are useful for treating a number of disorders, including pancreatic, colorectal, and lung cancers.

Design, synthesis of 6-substituted-pyrido[3,2-d]pyridazine derivatives with anticonvulsant activity

Aim to find new compounds with stronger anticonvulsant activity and lower neurotoxicity, a novel series of 6-substituted-pyrido[3,2-d]pyridazine derivatives was synthesized using furo[3,4-b]pyridine-5,7-dione as the starting material. We evaluated their a

Addressing PXR liabilities of phthalazine-based hedgehog/smoothened antagonists using novel pyridopyridazines

Pyridopyridazine antagonists of the hedgehog signaling pathway are described. Designed to optimize our previously described phthalazine smoothened antagonists, a representative compound eliminates a PXR liability while retaining potency and in vitro metab

ANNELATED PYRIDAZINES FOR THE TREATMENT OF TUMORS DRIVEN BY INAPPROPRIATE HEDGEHOG SIGNALLING

The present invention relates generally to compounds represented in Formula (I), pharmaceutical compositions comprising them and methods of treating of diseases or disorders such as cancer.

Pentaaza-cyclopental[a]naphthalene derivatives as ligands for GABAa α5 receptors

A class of 1,2,3a,4,x-pentaaza-cyclopenta[a]naphthalene compounds (x=6, 7, 8 or 9) is described. The compounds have a high affinity for the GABAAα5 receptors and show inverse agonist activity thereat. The compounds are useful in therapy where cognition enhancement is required.

6-Chloro-1,2,4-triazolopyrido- and pyridazines - Synthesis and Structure determination

5,8-Dichloropyridopyridazine (2) gave with hydrazine hydrate in dioxane 5-chloro-8-hydrazino- and 8-chloro-5-hydrazinopyridopyridazines 3 and 4.When 3 and 4 were allowed to react with formic acid they gave a mixture of the 6-chloro-1,2,4-triazolopyrido- and pyridazines (5 and 6).