7032-86-2Relevant academic research and scientific papers
C-H Functionalization of Amino Alcohols by Osmium Tetroxide/NMO or TPAP/NMO: Protecting Group-Free Synthesis of Indolizidines (–)-223AB and 3-epi-(–)-223AB
Chen, Wei-Lun,Wang, Lee-Ya,Li, Yu-Jang
supporting information, p. 103 - 107 (2020/01/02)
The oxidative cyclization of amino alcohols by osmium tetroxide/NMO or tetrapropylammonium perruthenate (TPAP)/NMO was found to provide an N,O-acetal moiety through the trapping of the resulting iminium ion by the alcohol. These two transformations were demonstrated in the synthesis of indolizidines (–)-223AB and 3-epi-(–)-223AB.
Aminolysis of Oxetanes: Quite Efficient Catalysis by Lanthanide(III) Trifluoromethansulfonates
Crotti, Paolo,Favero, Lucilla,Macchia, Franco,Pineschi, Mauro
, p. 7089 - 7092 (2007/10/02)
Ln(III)trifluoromethansulfonates in CH2Cl2 efficiently catalyze the aminolysis of trimethylene oxide, 2-octyl-, and 2-phenyloxetane, at r.t., to give the corresponding γ-amino alcohols in very good yields.
