70372-38-2

Upstream product

• 622-97-9 1-ethenyl-4-methylbenzene 
• 505-14-6 thiocyanogen 
• 64-19-7 acetic acid 
• 2051-59-4 6-Chloro-chromen-2-one 
• 333-20-0 potassium thioacyanate 
• 540-72-7 sodium thiocyanide 
• 1147550-11-5 ammonium thiocyanate 

Relevant academic research and scientific papers

Peroxodisulfate-assisted three-component benzylation of coumarins with styrenes and KSCN: a transition-metal-free approach for the synthesis of 3-(1-aryl-2-thiocyanatoethyl)-2H-chromen-2-one in ethyl lactate

Peroxodisulfate-assisted three-component benzylation of coumarins with styrenes and KSCN to 3-(1-aryl-2-thiocyanatoethyl)-2H-chromen-2-one is reported for the first time. This reaction proceedsviathe consecutive addition of the SCN radical to styrenes followed by the addition of the resultant substituted-benzylic radical to the C3-position of coumarin derivatives. In contrast to previous approaches that normally require transition-metal catalysis, toxic volatile organic solvents, bases and elevated temperature, the present strategy of benzylation of coumarins is transition-metal-free and base-free, and applicable under ambient conditions with ethyl lactate as a green medium.

Copper Nitrate-Mediated Selective Difunctionalization of Alkenes: A Rapid Access to β-Bromonitrates

A regioselective copper nitrate-mediated difunctionalization of alkenes has been developed for the rapid synthesis of β-bromonitrates, where copper nitrate is used as an ideal nitrooxy source for the first time and the products will find many applications in organic synthesis as versatile synthons. Different from the general reports that copper nitrate acts as the nitro source, the given protocol provides a direct access to functionalized nitrates, with operational simplicity, good functional group tolerance and a wide substrate scope. (Figure presented.).

Ferric(III) chloride-promoted efficient thiocyanation of arylalkenes: A facile synthesis of dithiocyanates

Anhydrous FeCl3 oxidizes potassium thiocyanate to the corresponding radical and promotes subsequent addition to nucleophilic olefins to produce dithiocyanate derivatives under mild conditions with high efficiency. Excellent yields and chemosele

Cerium(IV) ammonium nitrate mediated addition of thiocyanate and azide to styrenes: Expeditious routes to phenacyl thiocyanates and phenacyl azides

An efficient synthesis of phenacyl thiocyanates and phenacyl azides is described here. Styrenes react with ammonium thiocyanate and sodium azide in the presence of cerium(IV) ammonium nitrate under an oxygen atmosphere to afford phenacyl thiocyanates and phenacyl azides respectively in good yields. (C) 2000 Published by Elsevier Science Ltd.

A very efficient Cerium (IV) ammonium nitrate (CAN) mediated thiocyanation of aralkenes: Formation of dithiocyanates

A facile dithiocyanation of aralkenes mediated by Cerium (IV) ammonium nitrate is described.

KINETICS AND DOPING EFFECT IN THE ADDITION OF 2,4-DINITROPHENYLSULFENYL CHLORIDE AND DITHIOCYANOGEN TO OLEFINS

The rate of the doping addition in the reactions of 2,4-dinitrophenylsulfenyl chloride with cyclohexene an methylenecyclobutane and of dithiocyanogen with cyclohexene and substituted styrenes in the presence of lithium perchlorate is described by the normal salt effect equation.On the other hand, the rate of formation of the doping products may exceed or lag behind the increase in the total reaction rate.These results were interpreted in the framework of an ion-pair mechanism.