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70380-73-3 Usage

General Description

5-(2-Pyridyl)-1,3-oxazole is a chemical compound with the molecular formula C9H7N2O. It is a heterocyclic organic compound containing a pyridine ring and an oxazole ring. 5-(2-PYRIDYL)-1,3-OXAZOLE is commonly used in pharmaceutical and organic synthesis, as it serves as a building block for various pharmaceutical drugs and fine chemicals. It exhibits biological activities such as antibacterial, antifungal, and anticancer properties, making it a valuable compound in drug development. Additionally, it is used as a fluorescent indicator in analytical chemistry and as a ligand in coordination chemistry. This chemical is flammable and should be handled with care in a controlled laboratory environment.

Check Digit Verification of cas no

The CAS Registry Mumber 70380-73-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,0,3,8 and 0 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 70380-73:
113 % 10 = 3
So 70380-73-3 is a valid CAS Registry Number.

70380-73-3 Well-known Company Product Price

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  • Alfa Aesar

  • (H34123)  5-(2-Pyridyl)-1,3-oxazole, 97%   

  • 70380-73-3

  • 250mg

  • 840.0CNY

  • Detail
  • Alfa Aesar

  • (H34123)  5-(2-Pyridyl)-1,3-oxazole, 97%   

  • 70380-73-3

  • 1g

  • 2338.0CNY

  • Detail
  • Alfa Aesar

  • (H34123)  5-(2-Pyridyl)-1,3-oxazole, 97%   

  • 70380-73-3

  • 5g

  • 7504.0CNY

  • Detail



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017


1.1 GHS Product identifier

Product name 5-pyridin-2-yl-1,3-oxazole

1.2 Other means of identification

Product number -
Other names 2-oxazol-5-yl-pyridine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:70380-73-3 SDS

70380-73-3Relevant articles and documents

Convergent and Practical Synthesis of Fluorescent Triphenylamine Derivatives and Their Localization in Living Cells

Auvray, Marie,Franck, Xavier,Gallavardin, Thibault,Leleu, Stéphane,Mahuteau-Betzer, Florence,Mougeot, Romain,Oger, Samuel

supporting information, (2022/02/09)

In the search for new fluorescent triphenylamine (TP) derivatives, we studied the influence of the position and substitution of diverse heterocyclic substituents. A library of 10 fluorescent triphenylamines bearing either oxazoles or thiazoles and pyridiniums, substituted at different positions has been developed. The approach is based on a convergent C?H activation reaction between pyridine-oxazoles or pyridine-thiazoles and di-iodo triphenylamine. We showed that the nature and substitution pattern of the 5-membered- (oxazole, thiazole) or 6-membered heterocycle (pyridine) has a strong influence on their fluorescence properties and on their localization in living cells as they stain either the nucleus or mitochondria.

Improvement of the Van Leusen reaction in the presence of β-cyclodextrin: A green and efficient synthesis of oxazoles in water

Rahimzadeh, Golnaz,Kianmehr, Ebrahim,Mahdavi, Mohammad

, p. 923 - 926 (2017/12/18)

An efficient approach for the synthesis of oxazoles through the Van Leusen reaction in the presence of β-cyclodextrin is described. In aqueous medium using β-cyclodextrin as a supramolecular catalyst, tosylmethyl isocyanide was deprotonated by triethylami

Linear and Branched Pyridyl-Oxazole Oligomers: Synthesis and Circular Dichroism Detectable Effect on c-Myc G-Quadruplex Helicity

Rizeq, Natalia,Georgiades, Savvas N.

, p. 122 - 131 (2016/01/26)

Five unprecedented pyridyl-oxazole oligomers exhibiting either linear or branched connectivity of their subunits were developed as a family of potential G-quadruplex-interacting ligands. Our synthesis employed variations of a key Pd/Cu-mediated C-C cross-coupling/C-H activation reaction to gain access to the oligomer products from a small set of substituted pyridine building blocks. The effect of the compounds on the conformation of a c-myc oncogene promoter G-quadruplex was investigated by circular dichroism under various conditions. Some or all of the compounds induced detectable helicity enhancement in low-cation and Na+-rich Tris-HCl (pH 7.4) buffers, respectively, in which the helix was only partially prefolded.

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