70415-70-2Relevant academic research and scientific papers
Chelation-accelerated sequential decarbonylation of formate and alkoxycarbonylation of aryl halides using a combined Ru and Pd catalyst
Ko, Sangwon,Lee, Chongmok,Choi, Moon-Gun,Na, Youngim,Chang, Sukbok
, p. 1607 - 1610 (2003)
An efficient cooperative catalyst system for the coupling of a wide range of organic electrophiles with chelated formate is reported to afford aryl and alkenyl esters by the simultaneous employment of Ru and Pd catalyst, in which ruthenium first promotes chelation-accelerated decarbonylation of formate to release CO and carbinol that are presumed to be transferred, still chelated to Ru, into Pd catalyst, which catalyzes alkoxycarbonylation of the organic electrophiles.
Synthesis of 2-Pyridinemethyl Ester Derivatives from Aldehydes and 2-Alkylheterocycle N-Oxides via Copper-Catalyzed Tandem Oxidative Coupling-Rearrangement
Wang, Chang-Sheng,Roisnel, Thierry,Dixneuf, Pierre H.,Soulé, Jean-Fran?ois
supporting information, p. 6720 - 6723 (2017/12/26)
Successful benzylic C(sp3)-H acyloxylation of 2-alkylpyridine, 2-alkylpyrazine, and 2-alkylthiazole compounds was achieved using simple aldehydes. This was carried out via a copper-catalyzed tandem reaction, involving oxidative esterification followed by O-atom transfer of the resultant high yield formed Boekelheide intermediate. The method enables the preparation of functional heterocycles and the desymmetrization of 2,6-dialkylpyridines for efficient synthesis of dissymmetric pincer ligands, thus offering a new life for more practical Boekelheide rearrangement.
