70415-72-4Relevant academic research and scientific papers
Nickel-catalyzed alkoxycarbonylation of aryl iodides with 1 atm CO
Liu, Ning,Wu, Xianqing,Wang, Chenglong,Qu, Jingping,Chen, Yifeng
supporting information, p. 4643 - 4646 (2022/04/19)
A nickel-catalyzed alkoxycarbonylation of aromatic iodides with alcohols under atmospheric pressure of carbon monoxide is presented here. This operationally simple protocol allows the facile synthesis of (hetero)aromatic esters, exhibiting broad substrate scope with excellent functional group tolerance. Various primary and secondary aliphatic alcohols as well as phenols are suitable for this transformation.
Ligand-Free Copper(I)-Catalyzed Benzylic Acyloxylation of 2-Alkylpyridines under Aerobic Conditions
Cheng, Li,Sun, Yuqian,Wang, Wenrong,Yao, Changsheng,Li, Tuan-Jie
, p. 3074 - 3082 (2019/03/11)
A ligand-free copper(I)-catalyzed benzylic acyloxylation of 2-alkylpyridines with carboxylic acids was realized by using 1.0 atm of O2 as a green oxidant. The transformation provided a facile access to a wide range of N-heterocyclic esters thro
Practical: In situ -generation of phosphinite ligands for palladium-catalyzed carbonylation of (hetero)aryl bromides forming esters
Wang, Lin,Neumann, Helfried,Spannenberg, Anke,Beller, Matthias
, p. 7469 - 7472 (2017/07/12)
An effective method for alkoxycarbonylation of (hetero)aryl bromides is developed in the presence of in situ-generated phosphinite ligands tBu2POR (R = nBu, nPr, Et or Me). For this purpose commercially available tBu2PCl was used as the pre-ligand in the presence of different alcohols. For the first time cross coupling reactions with two alcohols-one generating the ligand, the other used as substrate-were developed. Through this method, ligand optimization can be performed in a more efficient manner and the desired products could be obtained with good yields and selectivity.
Chelation-accelerated sequential decarbonylation of formate and alkoxycarbonylation of aryl halides using a combined Ru and Pd catalyst
Ko, Sangwon,Lee, Chongmok,Choi, Moon-Gun,Na, Youngim,Chang, Sukbok
, p. 1607 - 1610 (2007/10/03)
An efficient cooperative catalyst system for the coupling of a wide range of organic electrophiles with chelated formate is reported to afford aryl and alkenyl esters by the simultaneous employment of Ru and Pd catalyst, in which ruthenium first promotes chelation-accelerated decarbonylation of formate to release CO and carbinol that are presumed to be transferred, still chelated to Ru, into Pd catalyst, which catalyzes alkoxycarbonylation of the organic electrophiles.
