70439-96-2

Usage

Uses

Used in Chemical Synthesis Industry:
2,3,5,6-Tetrachloro-4-methoxyaniline is used as a key intermediate for the production of various dyes and pigments, contributing to the coloration and stability of these products in different applications.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, 2,3,5,6-Tetrachloro-4-methoxyaniline serves as a precursor in the synthesis of certain drugs, playing a crucial role in the development of new medicinal compounds.
However, due to its toxic nature and potential health hazards, including skin, eye, and respiratory irritation, as well as its classification as a hazardous substance with possible environmental impacts, strict safety measures and precautions are necessary when handling and using 2,3,5,6-Tetrachloro-4-methoxyaniline in industrial or research settings.

InChI:InChI=1/C7H5Cl4NO/c1-13-7-4(10)2(8)6(12)3(9)5(7)11/h12H2,1H3

Upstream product

• 77218-84-9 N-(2,3,5,6-tetrachloro-4-methoxyphenyl)acetamide 
• 4877-71-8 2,3,5,6-Tetrachlor-4-fluor-anilin 
• 124-41-4 sodium methylate 
• 32407-11-7 3,5-dichloro-4-methoxyaniline 
• 17742-69-7 2,6-dichloro-4-nitro-anisole 
• 6936-40-9 2,3,5,6-tetrachloroanisole 
• 386-60-7 1-Fluor-4-nitrotetrachlorbenzol 

Downstream Products

• 6936-40-9 2,3,5,6-tetrachloroanisole 
• 484-67-3 Drosophilin A 
• 84756-46-7 4-iodo-2,3,5,6-tetrachloroanisole 
• 5134-79-2 4-Diazo-2,3,5,6-tetrachlorocyclohexa-2,5-diene-1-one 
• 5533-10-8 2,3,5,6-tetrachlorohydroquinone diacetate 

Relevant academic research and scientific papers

Identification of hydroxylated PCB metabolites and other phenolic halogenated pollutants in human blood plasma

A growing number of studies have reported phenolic halogenated compounds (PHCs) that are retained in the blood of humans and wildlife. These PHCs may be industrial chemicals; metabolites thereof, as in the case with polychlorobiphenylols (OH-PCBs); or of natural origin. The present study was aimed to identify hitherto unknown PHCs in human plasma with chemical structures that are consistent to PHCs known to possess endocrine-disrupting activity. For this purpose, samples of blood plasma from 10 randomly selected male blood donors from Sweden were pooled and analyzed by GC/ECD and GC/MS. Brominated, bromochlorinated, and chlorinated methyl derivatives of phenols and OH-PCBs were synthesized to be used as authentic reference standards. More than 100 PHCs were indicated in the plasma, and among those a total of 9 monocyclic brominated or chlorinated phenol-, guaiacol-, and/or catechol-type compounds were identified as their methylated derivatives. The two major compounds were 2,4,6-tribromophenol and pentachlorophenol. Thirty-eight OH-PCB congeners were structurally identified on two GC columns of different polarity. The origin of the OH-PCB metabolites in the context of their parent PCB congeners are suggested. Other PHCs identified in the male plasma were Triclosan (5-chloro-2-[2,4-dichlorophenoxy] phenol), a common bactericide; 4-hydroxy-heptachlorostyrene, a metabolite of octachlorostyrene; and 3,5-dibromo-2-(2,4-dibromophenoxy)phenol, a natural compound and a potential metabolite of polybrominated diphenyl ethers.