70465-61-1

Basic information

• Product Name: N4-ETHYL-2'-DEOXYCYTIDINE
• Synonyms: N4-ETHYL-2'-DEOXYCYTIDINE
• CAS NO: 70465-61-1
• Molecular Formula: C₁₁H₁₇N₃O₄
• Molecular Weight: 255.27
• Mol File: 70465-61-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 466.7 °C at 760 mmHg
• Flash Point: 236.1 °C
• Appearance: /
• Density: 1.49 g/cm3
• Solubility: DMSO (Slightly)
• PKA: 14.03±0.60(Predicted)
• CAS DataBase Reference: N4-ETHYL-2'-DEOXYCYTIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: N4-ETHYL-2'-DEOXYCYTIDINE(70465-61-1)
• EPA Substance Registry System: N4-ETHYL-2'-DEOXYCYTIDINE(70465-61-1)

Safety Data

• Hazardous Substances Data: 70465-61-1(Hazardous Substances Data)

Usage

Uses

N4-Ethyl-2’-deoxycytidine avoids self-dimerization of fluorescent DNA probes.

Upstream product

• 103931-23-3 3’,5’-bis-O-acetyl-4-thio-2’-deoxyuridine 
• 32909-05-0 N⁴-acetyl-2'-deoxycytidine 
• 109-89-7 diethylamine 
• 75-04-7 ethylamine 

Downstream Products

• 1377950-52-1 N⁽⁴⁾-acetyl-O(3')-CEP-O(5')-DMT-N⁽⁴⁾-ethyl-dC 
• 1377950-50-9 N⁽⁴⁾-acetyl-O(5')-DMT-N⁽⁴⁾-ethyl-dC 
• 195535-75-2 O(5')-DMT-N⁽⁴⁾-ethyl-dC 

Relevant articles and documents

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Transformations of thiopyrimidine and thiopurine nucleosides following oxidation with dimethyldioxirane

A general and convenient method for the synthesis of several pyrimidine and purine nucleosides by selective oxidation of thionucleosides with dimethyldioxirane is reported. Thioketo moieties in the C-4 position of the pyrimidine ring, and in the C-6, and C-8 positions of the purine ring are the domain of oxidative nucleophilic substitution. Thioketo moieties in the C-2 position of both purine and pyrimidine rings are the domain of desulfurization or formation of disulfides.