7048-98-8Relevant academic research and scientific papers
Synthesis of [n]- and [n.n]Cyclophanes by using Suzuki-Miyaura coupling
Smith, Beverly B.,Hill, Darron E.,Cropp, T. Ashton,Walsh, Rosa D.,Cartrette, David,Hipps, Sherry,Shachter, Amy M.,Pennington, William T.,Kwochka, William R.
, p. 5333 - 5337 (2007/10/03)
Reaction of the bis-9-BBN adduct of several dienes with 1,3-dibromobenzene via Suzuki coupling leads to a series of [n]metacyclophanes ranging in size from 10 to 17 atom members. In each case, two carbon-carbon bonds are formed in one reaction vessel. However, when the bis-9-BBN adduct of 1,5-hexadiene is coupled with a variety of aryl dihalides, larger [n.n]cyclophanes were formed in preference to the [n]cyclophanes. Four carbon-carbon bonds are formed in this instance. Single-crystal X-ray analyses of these [n.n]cyclophanes reveal interestingly shaped molecules with large cavities.
Synthesis and Dynamic Behaviour of - and Metacyclophanes
Takeshita, Michinori,Tsuge, Akihiko,Tashiro, Masashi
, p. 411 - 413 (2007/10/02)
The synthesis and structure of - and metacyclophanes 2, 4 are described.The reductive ring opening of the thiophene rings of metacyclo(2,4)- and -(2,5)thiophenophanes 1 and 3 by Raney-Ni affords the corresponding - and metacyclophanes 2
Cyclophanes, XXI. The Chemical Behavior of Paracyclophane: Reactions of the Benzene Ring
Noble, Karl-Ludwig,Hopf, Henning,Ernst, Ludger
, p. 455 - 473 (2007/10/02)
Preparative quantities of paracyclophane (1b) may be prepared from paracyclophane-3,6-dione (9) by Wolff-Kishner reduction.After a detailed dicussion of the 1H and 13C NMR spectra of 1b, its behavior in substitution and addition reactions is describ
Arenes Disubstituted with Primary Alkyl Groups from Xylylene Dianions
Bates, Robert B.,Ogle, Craig A.
, p. 3949 - 3952 (2007/10/02)
Xylenes were converted into dianions 1.Reaction of dianions 1 with dialkyl sulfates gave symmetrical dialkylbenzenes 2 (R = R'), while methyl iodide caused oxidative coupling followed by alkylation to give 8.Unsymmetrical dialkylbenzenes 2 (R =/= R') were made by an indirect route involving monoanions 9 and 11.Reactions of dianions 1 with dihalides gave cyclophanes o-3 (n = 5,6,9), m-3 (n = 8-10), and p-3 (n = 9-11) and cyclophanes o-4 (n = 2,5,7,9) and m-4 (n = 2,6,7).Dianion 5 from 2,6-lutidine was used to prepare nitrogen analogues of 2 (R = R') and m-3 (n = 8-10).
