70565-67-2Relevant academic research and scientific papers
Mesyloxy-group migration as the stereoselective preparation method of various functionalized olefins and its reaction mechanism
Yamazaki, Takashi,Hiraoka, Shuichi,Sakamoto, Johei,Kitazume, Tomoya
, p. 743 - 746 (2007/10/03)
It was demonstrated that mesylation of appropriate γ,γ-difluorinated allylic alcohols under usual conditions furnished the corresponding α,γ-difluorinated allylic mesylates, possibly by way of 1,3-mesyloxy-group migration after formation of the expected "normal" intermediates, γ,γ-difluorinated allylic mesylates. This rearrangement was conveniently applied to the construction of trisubstituted allylic alcohols, α,β-unsaturated esters, amides, or ketones in good to excellent chemical yields with exclusive E selectivities.
Synthesis of Carbon and Phosphorus Esters of α-Fluoro Alcohols
Vinson, Wayne A.,Prickett, Kathryn S.,Spahic, Bojana,Montellano, Paul R. Ortiz de
, p. 4661 - 4668 (2007/10/02)
Carbon and phosphorus esters of α-fluoro alcohols are promising functions for the construction of suicide substrates for esterases, phosphatases, and other enzymes.A route for the synthesis of substrates incorporating these hitherto inaccessible functiona
