70592-74-4

Usage

InChI:InChI=1/C20H19N/c21-20(15-16-7-3-1-4-8-16)19-13-11-18(12-14-19)17-9-5-2-6-10-17/h1-14,20H,15,21H2

Upstream product

• 67680-92-6 N-(1-Biphenyl-4-yl-2-phenyl-ethyl)-formamide 
• 67680-91-5 1-(biphenyl-4-yl)-2-phenylethanone oxime 
• 2001-23-2 1-(biphenyl-4-yl)-2-phenylethanone 
• 92-52-4 biphenyl 
• 103-80-0 phenylacetyl chloride 
• 3218-36-8 4-Phenylbenzaldehyde 
• 108-88-3 toluene 

Relevant academic research and scientific papers

Alkaline-metal-catalyzed one-pot aminobenzylation of aldehydes with toluenes

A novel and easily accessible MN(SiMe3)2 (M = Li or Na)/Cs2CO3 co-catalyzed benzylation of in situ generated N-(trimethylsilyl) aldimines with toluene derivatives has been successfully developed. The catalyst exhibits high chemoselectivity for deprotonation of toluenes at the benzylic position. The utility of this system is exemplified by the one-pot synthesis of a diverse array of bioactive 1,2-diarylethylamines with excellent efficiency and broad functional group tolerance.

New biphenyl derivatives I: 1-(4-biphenylyl)-2-phenylethylamines as potential antispasmodic and cardiovascular agents

A series of 1-(4-biphenylyl)-2-phenylethylamine derivatives was synthesized as potential antispasmodic and cardiovascular agents related to papaverine. Preliminary pharmacological tests, on isolated guinea pig ileum and anesthetized cat blood pressure, showed that the new compounds possess nonspecific inhibitory action on smooth muscles.