705967-79-9

Usage

Uses

Used in Pharmaceutical Research:
2-(4-Amino-2-oxo-1(2H)-pyrimidinyl)-1,5-anhydro-2-deoxy-4,6-O-[(R)-phenylmethylene]-D-altritol is used as a research compound for exploring its potential medicinal applications. Its unique structure and functional groups suggest that it may have therapeutic effects, which are currently under investigation.
Used in Drug Development:
In the pharmaceutical industry, 2-(4-Amino-2-oxo-1(2H)-pyrimidinyl)-1,5-anhydro-2-deoxy-4,6-O-[(R)-phenylmethylene]-D-altritol is utilized as a candidate for drug development. Its synthesis and characterization are crucial for understanding how it can be applied in the creation of new medications, particularly those targeting specific diseases or conditions.
Used in Chemical Research:
Beyond its medicinal applications, 2-(4-Amino-2-oxo-1(2H)-pyrimidinyl)-1,5-anhydro-2-deoxy-4,6-O-[(R)-phenylmethylene]-D-altritol is also used in broader chemical research. Its complex structure provides opportunities for studying chemical reactions and interactions that could lead to advancements in various fields of chemistry.

Upstream product

• 92283-88-0 1,5:2,3-dianhydro-4,6-O-benzylidene-D-allitol 
• 10310-21-1 2-amino-6-chloropurine 
• 68-12-2 N,N-dimethyl-formamide 
• 10310-21-1 2-Amino-6-chloropurin 

Downstream Products

• 705967-83-5 1,5-anhydro-4,6-O-benzylidene-2-deoxy-2-(guanin-9-yl)-D-altro-hexitol 
• 705967-85-7 1,5-anhydro-4,6-O-benzylidene-3-O-tert-butyldimethylsilyl-2-(N²-iso-butyrylguanin-9-yl)-2-deoxy-D-altro-hexitol 
• 705967-84-6 1,5-anhydro-4,6-O-benzylidene-2-(N²-iso-butyrylguanin-9-yl)-2-deoxy-D-altro-hexitol 

Relevant academic research and scientific papers

TETRAHYDROPYRAN NUCLEIC ACID ANALOGS

The present disclosure describes tetrahydropyran nucleoside analogs, oligomeric compounds prepared therefrom and methods of using the oligomeric compounds. More particularly, tetrahydropyran nucleoside analogs are provided, having one or more chiral subst

Synthesis of D-Altritol Nucleosides with a 3′ -O-Tert-Butyldimethylsilyl Protecting Group

Four D-altritol nucleosides with a 3′-O-tert- butyldimethylsilyl protecting group are synthesized (base moieties are adenine, guanine, thymine and 5-methylcytosine). The nucleosides are obtained by ring opening reaction of 1,5:2,3-dianhydro-4,6-O-benzylid

Synthesis of protected D-altritol nucleosides as building blocks for oligonucleotide synthesis

D-Altritol nucleosides with an adenine and uracil base moiety were obtained by nucleophilic opening of the epoxide ring of 1,5:2,3-dianhydro- 4,6-O-benzylidene-D-allitol using the sodium salt of the above mentioned bases. The use of a 2-trimethylsilylethyl protecting group for the O6- function of the guanine base offers a useful compromise between stability and acceptable alkylation yields of the N9-position if the guanine base. The cytosine nucleoside was synthesized starting from the uracil congener. The 3'-hydroxyl function was protected with a benzoyl group.