7064-06-4

Basic information

• Product Name: 4-methyl-2-oxo-5-[(4-oxo-3-propyl-2-thioxo-1,3-thiazolidin-5-ylidene)methyl]-1-propyl-6-pyrrolidin-1-yl-1,2-dihydropyridine-3-carbonitrile
• CAS NO: 7064-06-4
• Molecular Formula: C₁₀H₁₁NO
• Molecular Weight: 430.5867
• Mol File: 7064-06-4.mol
• Article Data: 21

Chemical Properties

• Boiling Point: 448.1°C at 760 mmHg
• Flash Point: 224.8°C
• Density: 1.33g/cm³
• Vapor Pressure: 3.19E-08mmHg at 25°C
• Refractive Index: 1.658
• CAS DataBase Reference: 4-methyl-2-oxo-5-[(4-oxo-3-propyl-2-thioxo-1,3-thiazolidin-5-ylidene)methyl]-1-propyl-6-pyrrolidin-1-yl-1,2-dihydropyridine-3-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methyl-2-oxo-5-[(4-oxo-3-propyl-2-thioxo-1,3-thiazolidin-5-ylidene)methyl]-1-propyl-6-pyrrolidin-1-yl-1,2-dihydropyridine-3-carbonitrile(7064-06-4)
• EPA Substance Registry System: 4-methyl-2-oxo-5-[(4-oxo-3-propyl-2-thioxo-1,3-thiazolidin-5-ylidene)methyl]-1-propyl-6-pyrrolidin-1-yl-1,2-dihydropyridine-3-carbonitrile(7064-06-4)

Safety Data

• Hazardous Substances Data: 7064-06-4(Hazardous Substances Data)

Upstream product

• 100-42-5 styrene 
• 79-24-3 Nitroethane 
• 683-58-9 acetohydroximoyl chloride 
• 3145-76-4 (2-methylcyclopropyl)benzene 
• 77252-92-7 3-ethoxy-1-phenyl-but-2-en-1-one 
• 4866-54-0 (2-methyl-cyclopropyl)-benzene 
• 7063-95-8 acetonitrile-N-oxide 
• 55134-78-6 3-methyl-5-phenyl-2-trimethylsilanyloxy-isoxazolidine 
• 107-29-9 Acetaldehyde oxime 
• 89762-98-1 anti-3-benzyloxyimino-1-phenyl-1-butanol 
• 5381-93-1 1-hydroxy-1-phenyl-3-butanone 
• 89762-93-6 syn-3-benzyloxyimino-1-phenyl-1-butanol 
• 83996-13-8 1-phenyl-3-(p-methyl)phenoxy-2-buten-2-one 
• 83996-14-9 1-phenyl-3-(1-imidazolyl)-2-buten-1-one 

Downstream Products

• 124852-33-1 (R^*,5R^*)-3-methyl-3,5-diphenylisoxazolidine 
• 1567-89-1 N-(2,4-dinitrophenyl)-N'-isopropylidene-hydrazine 
• 1157-84-2 1-benzylidene-2-(2,4-dinitrophenyl)hydrazone 
• 73661-54-8 3,4-Dimethyl-5-phenyl-2-isoxazolin 
• 55134-83-3 5-phenyl-3-ethyl-Δ²-isoxazoline 
• 73661-54-8 (4S,5R)-3,4-Dimethyl-5-phenyl-4,5-dihydro-isoxazole 
• 5381-93-1 1-hydroxy-1-phenyl-3-butanone 
• 66417-92-3 4-phenyl-2-butanone oxime 
• 127707-63-5 2-phenyl-2-hydroxyethyl acetate 
• 127707-64-6 2-hydroxy-1-phenylethyl acetate 
• 100-52-7 benzaldehyde 
• 67-64-1 acetone 
• 1896-62-4 (E)-benzalacetone 
• 73406-39-0 c-4-Methyl-c-6-phenyl-r-2-(4-nitrophenyl)tetrahydro-1,3-oxazin 

Relevant articles and documents

Study of the Features of the Reaction of Arylcyclopropanes with Nitrozonium Ethyl Sulfate or Nitrozonium Tetrafluoroborate

Abstract: The reactions of diaryl-, aryl-, and alkyl–arylcyclopropanes with ethyl nitrite in the presence of sulfur trioxide and sulfur trioxide dioxane complex, as well as the reactions of 1-alkyl-2-arylcyclopropanes with NOBF4 were studied. It was found that the attack of the nitrosonium cation, accompanied by the formation of a benzyl carbocation, leads to the formation of isoxazolines. The introduction of bulky alkyl substituents into the cyclopropane ring changes the regioselectivity of nitrosation, favoring the attack of the electrophilic particle on the benzyl position and leading to the competitive formation of an alkyl carbocation. Depending on the structure of the alkyl substituent, both products of intramolecular heterocyclization accompanied by skeletal rearrangements and products formed with the participation of an external nucleophile are formed.

Δ2-isoxazolines from arylcyclopropanes: III. Phenylcyclopropanes substituted in three-membered ring in reaction with nitrosyl chloride activated with oxides of sulfur(IV, VI)

The reaction of phenylcyclopropanes substituted in the three-membered ring with nitrosyl chloride activated with sulfur(IV, VI) oxides provided in good yield substituted 5-phenylisoxazolines as a mixture of structural isomers.

4,5-Dihydroisoxazoles by copper(II)-catalysed condensation of primary nitroalkanes with dipolarophiles

Primary aliphatic nitro compounds condense with substituted alkenes to give 4,5-dihydroisoxazoles under copper(II) acetate catalysis in the presence of tertiary amines. Apparently nitrile oxides are not intermediates, as no furoxans are detected in these