70657-70-4

Basic information

• Product Name: 2-methoxypropyl acetate
• Synonyms: 1-Propanol, 2-methoxy-, acetate;2-methoxypropyl-1-acetate;BETA-PROPYLENEGLYCOLMONOMETHYLETHERACETATE;2-METHOXY-1-PROPYLACETATE;1-PROPYLENEGLYCOL-2-METHYLETHERACETATE;2-methoxy-1-propano acetat;propylene glycol monomethyl ether acetate, beta-isomer;2-Mepa
• CAS NO: 70657-70-4
• Molecular Formula: C₆H₁₂O₃
• Molecular Weight: 132.16
• EINECS: 274-724-2
• Mol File: 70657-70-4.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 184.08°C (rough estimate)
• Flash Point: 47.9℃
• Appearance: /
• Density: 0.96(20.0000℃)
• Vapor Pressure: 3.13mmHg at 25°C
• Refractive Index: 1.4730 (estimate)
• CAS DataBase Reference: 2-methoxypropyl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methoxypropyl acetate(70657-70-4)
• EPA Substance Registry System: 2-methoxypropyl acetate(70657-70-4)

Safety Data

• Hazard Codes: T
• Statements: 61-10-37
• Safety Statements: 53-45-24/25
• RIDADR: 1993
• HazardClass: 3.2
• PackingGroup: III
• Hazardous Substances Data: 70657-70-4(Hazardous Substances Data)

Usage

General Description

2-methoxypropyl acetate, also known as propylene glycol monomethyl ether acetate, is a solvent commonly used in various industrial applications. It is a clear, colorless liquid with a mild odor, and it is soluble in water and most organic solvents. 2-methoxypropyl acetate is commonly used as a solvent in the manufacturing of paints, coatings, and inks, as well as in the production of adhesives, sealants, and cleaning products. It is also used as a solvent for cellulose acetate, natural resins, and synthetic polymers. Additionally, it has low volatility and high solvency, making it an effective solvent for a wide range of applications. However, it is important to use 2-methoxypropyl acetate in a well-ventilated area and with proper safety precautions, as it can be harmful if inhaled or ingested.

InChI:InChI=1/C6H12O3/c1-5(8-3)4-9-6(2)7/h5H,4H2,1-3H3

Synthetic route

2-methoxypropanol (1589-47-5) + acetic acid (64-19-7) → propylene glycol monomethyl acetate (70657-70-4)

Conditions	Yield
With hydrogenchloride In water at 80 - 150℃;
With 1-butyl-3-methylimidazolium hydrogen sulfate; cyclohexane at 75 - 150℃; for 4h; Reagent/catalyst; Temperature;

2-methoxypropanol (1589-47-5) + acetic anhydride (108-24-7) → propylene glycol monomethyl acetate (70657-70-4)

Conditions	Yield
With phosphoric acid at 80 - 150℃;

[1,3]-dioxolan-2-one (96-49-1) + aminobutyraldehyde dimethyl acetal (102878-90-0) + propylene glycol monomethyl acetate (70657-70-4) → 1-ethyl-4-(hydroxymethyl)-2,6,7-trioxabicyclo-[2.2.2]-octane (74358-92-2)

Conditions	Yield
With potassium hydroxide

Upstream product

• 1589-47-5 2-methoxypropanol 
• 108-24-7 acetic anhydride 
• 64-19-7 acetic acid 

Relevant articles and documents

An acidic ion liquid catalytic synthesis of 2 - methoxy - 1 - propanol acetate method (by machine translation)

The invention discloses an acidic ionic liquid catalytic synthesis of 2 - methoxy - 1 - propanol acetate method, characterized in that in order to 2 - methoxy - 1 - propanol with acetic acid as the raw material, the acidic ionic liquid catalyst 1 - butyl - 3 - methyl imidazole bisulfate and cyclohexane under the action of a dehydrating agent, esterification and dewatering synthesis of 2 - methoxy - 1 - propanol acetate, wherein catalyst consumption is 2 - methoxy - 1 - propanol with the quality of the acetate 0.2 - 8%; 2 - methoxy - 1 - propanol with acetic acid in a molar ratio of 1:1 - 3; the esterification reaction temperature 75 - 150 °C, water produced during the esterification reaction with the cyclohexane azeotropic distillation for removing; the esterification reaction product of rectification to obtain 2 - methoxy - 1 - propanol acetate, after rectifying the residue containing catalyst and partial 2 - methoxy - 1 - propanol acetate recycled. The method of the invention the activity of the catalyst is high, good stability, corrosion of equipment is low, the catalyst can be recycled. (by machine translation)