70659-86-8

Usage

InChI:InChI=1/C12H25NO/c1-4-5-6-7-8-9-12(14)13-10-11(2)3/h11H,4-10H2,1-3H3,(H,13,14)

Upstream product

• 6304-39-8 caprylic hydrazide 
• 78-81-9 isobutylamine 
• 124-07-2 Octanoic acid 
• 111-64-8 n-octanoic acid chloride 

Relevant academic research and scientific papers

Isobutyramide derivative and application thereof

The present invention relates to the technical field of cosmetics, and particularly relates to an isobutyramide derivative compound and an application thereof. The obtained compound can be used for preparing a cosmetic reagent or a pharmaceutical reagent by preparing the series compound which has antihistamine and inhibits skin erythema, pruritus and hyaluronidase. The cosmetic reagent and the pharmaceutical reagent are not specifically limited. For example, the reagents can be washing cosmetics such as skin softening lotion, nutritional lotion, massage cream, body lotion, gel, nutritional cream, facial masks and hair gel or bath cream shampoo, and also can be drug preparation products such as similar cream, ointment, cream, plaster or spray; and when the compound is used for the sensitiveskin, infant and child cosmetics can be also added with the compound to reduce irritation.

ALKAMIDE COMPOUNDS AND USES THEREOF

The present disclosure relates to alkamide compounds and compositions for treating allergic diseases, pain, or itch.

Antifungal agent, antimildew method using the same, and a method using the growth inhibiting growth inhibiting agent

PROBLEM TO BE SOLVED: To provide a mould-proofing agent exhibiting highly mould-proofing effect and enabling its own production cost to be reduced, and to provide a mould-proofing method using the same.SOLUTION: The mould-proofing agent is provided, which includes an amide compound represented by general formula (1) as an active ingredient. In general formula (1), either one of Xand Xis 3-7C branched alkyl, the other being H; alternatively, the Xand Xare optionally bound to each other to form a (substituted) saturated or unsaturated 5- or 6-membered ring; Y is a 4-7C alkylene group; and Z is methyl or vinyl.

Synthesis and biological evaluation of a series of fatty acid amides from Echinacea

Abstract Alkylamides are lipophilic constituents of Echinacea and possess numerous biological activities. Although significant effort has been focused on the study of crude Echinacea extracts, very little is known regarding the activities of the individual constituents that make up these herbal treatments. Herein we explore the SAR of simple alkylamides found in Echinacea extracts with respect to their ability to decrease the production of the pro-inflammatory mediator TNF-α. Our results have revealed the key structural requirements for activity and provide lead compounds for further investigation of these poorly understood molecules.

GC/MS investigations of the minor constituents of Piper guineense stem

Chemical investigations by GC/MS-analysis of stem extracts of Piper guineense resulted in the detection and identification of thirty-nine new constituents of the stem, apart from previously isolated constituents. These are isobutyl, pyrrolidyl and piperidyl amide alkaloids. Fifteen new natural products have been identified. Four of these natural products have been designated iyeremide A and B (these are pyrrolidine and piperidine analogues of pellitorine) and cycloguineense A and B, which are also piperidine analogues of cyclostachine A and B. There is a need to confirm the structures of some of these new constituents by synthesis. Apart from these amide alkaloids, many volatile oil components-monoterpenes, sesquiterpenes, terpenoids, lignans and sterols - were detected.

FACILE OXIDATIVE CONVERSION OF HYDRAZIDES OF CARBOXYLIC ACIDS TO CORRESPONDING ACIDS, ESTERS AND AMIDES USING COPPER COMPOUNDS

Oxidative conversion of hydrazides of carboxylic acids to acids, esters and amides using Cu salts was studied.Acids were obtained in high yields by using a catalytic amount of Cu(OAc)2 at room temperature by bubbling oxygen.Hydrazides were converted to esters by the treatment with Cu(OR)Cl or Cu(OR)2 formed in situ from CuCl2 and sodium alkoxide.Amides were obtained in high yields by the oxidation of hydrazides with CuCl2 in the presence of amines.