706785-47-9Relevant academic research and scientific papers
Concise total synthesis of the thiazolyl peptide antibiotic GE2270 A
Delgado, Oscar,Martin Mueller,Bach, Thorsten
experimental part, p. 2322 - 2339 (2009/04/10)
The potent antibiotic thiazolylpeptide GE2270 A was synthesized starting from N-tert-butyloxycarbonyl protected valine in a longest linear sequence of 20 steps and with an overall yield of 4.8 %. Key strategy was the assembly of the 2,3,6-trisubstituted p
Total synthesis of the thiazolyl peptide GE2270 A
Mueller, H. Martin,Delgado, Oscar,Bach, Thorsten
, p. 4771 - 4774 (2008/02/10)
(Chemical Equation Presented) When one door closes, another opens: In the synthesis of the thiazolyl peptide GE2270 A (1), the bonds labeled I and II at the pyridine core were established by two consecutive cross-coupling reactions. Amide bond formation (
Total synthesis of the thiopeptide antibiotic amythiamicin D
Hughes, Rachael A.,Thompson, Stewart P.,Alcaraz, Lilian,Moody, Christopher J.
, p. 15644 - 15651 (2007/10/03)
The thiopeptide (or thiostrepton) antibiotics are a class of sulfur containing highly modified cyclic peptides with interesting biological properties, including reported activity against MRSA and malaria. Described herein is the total synthesis of the thi
Total synthesis of the thiopeptide amythiamicin D.
Hughes, Rachael A,Thompson, Stewart P,Alcaraz, Lilian,Moody, Christopher J
, p. 946 - 948 (2007/10/03)
The first total synthesis of the thiopeptide antibiotic amythiamicin D is described.
