706789-06-2

Usage

Uses

Used in Pharmaceutical Industry:
(2-CHLOROOXAZOL-4-YL)METHANOL is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its reactivity and stability allow for the development of new drugs with improved efficacy and safety profiles.
Used in Agrochemical Industry:
In the agrochemical sector, (2-CHLOROOXAZOL-4-YL)METHANOL serves as an essential component in the production of pesticides and other crop protection agents. Its versatile reactivity enables the creation of novel agrochemicals with enhanced performance and selectivity.
Used in Fine Chemicals Synthesis:
(2-CHLOROOXAZOL-4-YL)METHANOL is utilized as a building block in the synthesis of fine chemicals, including fragrances, dyes, and specialty chemicals. Its compatibility with various functional groups allows for the development of innovative and high-quality products.
Used in Organic Synthesis:
As a versatile reagent, (2-CHLOROOXAZOL-4-YL)METHANOL is employed in various organic synthesis reactions, such as esterification, alkylation, and acylation. Its stability and compatibility with a wide range of functional groups make it a valuable tool for chemists in designing and synthesizing complex organic molecules.

InChI:InChI=1/C4H4ClNO2/c5-4-6-3(1-7)2-8-4/h2,7H,1H2

Upstream product

• 934236-35-8 methyl 2-chlorooxazole-4-carboxylate 
• 706789-07-3 2-chlorooxazole-4-carboxylic acid 
• 460081-18-9 ethyl 2-chloro-1,3-oxazole-4-carboxylate 

Downstream Products

• 706789-08-4 4-bromomethyl-2-chlorooxazole 

Relevant academic research and scientific papers

ANDROGEN RECEPTOR MODULATORS AND METHODS FOR THEIR USE

The present invention relates to compounds of formula (I)-(VI) and/or (A)-(H-I), or any subgenera thereof, or a pharmaceutically acceptable salt, tautomer or stereoisomer. The compounds of the present disclosure are useful in modulating androgen receptor activity and for treating cancer including prostate cancer.

NOVEL COMPOUNDS FOR INHIBITION OF JANUS KINASE 1

An object of the invention is to provide compounds as selective JAK1 inhibitor, a process for preparation of the inhibitors, a composition containing the compounds and utility of the compounds.

Phenyl-oxazoles, a new family of inverse agonists at the H3 histamine receptor

(Chemical Equation Presented) Drug design: Oxazoles and thiazoles were designed and synthesised based on previously reported ligands of the 3rd histamine receptor (H3R). The aminopropoxy-phenyl-oxazole chemotype was identified as a promising H

4-Bromomethyl-2-chlorooxazole - A versatile oxazole cross-coupling unit for the synthesis of 2,4-disubstituted oxazoles

The synthesis of the novel oxazole building block, 4-bromomethyl-2- chlorooxazole, and its palladium-catalysed cross-coupling reactions to make a range of 2,4-disubstituted oxazoles, is described. Selectivity for the 4-bromomethyl position is observed, with Stille coupling effected in good to excellent yields, or Suzuki coupling in moderate yields, to provide a range of 4-substituted-2-chlorooxazoles. Subsequent coupling at the 2-chloro-position can be achieved through either Stille or Suzuki reactions in excellent yields.