70680-93-2 Usage
General Description
3-Chloro-L-tyrosine is a chemical compound that is derived from the amino acid tyrosine. It is classified as a chlorinated derivative of L-tyrosine and contains a chlorine atom attached to the carbon atom in the para position of the phenol ring. 3-CHLORO-L-TYROSINE is primarily used in organic synthesis for the creation of new pharmaceutical compounds and as a building block for other chemical reactions. It has also been studied for its potential therapeutic applications, particularly in the development of new anti-cancer agents and as a precursor for the synthesis of specific drugs. Overall, 3-Chloro-L-tyrosine has multiple potential uses in the field of medicinal chemistry and organic synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 70680-93-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,0,6,8 and 0 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 70680-93:
(7*7)+(6*0)+(5*6)+(4*8)+(3*0)+(2*9)+(1*3)=132
132 % 10 = 2
So 70680-93-2 is a valid CAS Registry Number.
70680-93-2Relevant articles and documents
Vinylation of Unprotected Phenols Using a Biocatalytic System
Busto, Eduardo,Simon, Robert C.,Kroutil, Wolfgang
, p. 10899 - 10902 (2015)
Readily available substituted phenols were coupled with pyruvate in buffer solution under atmospheric conditions to afford the corresponding para-vinylphenol derivatives while releasing only one molecule of CO2 and water as the by-products. This transformation was achieved by designing a biocatalytic system that combines three biocatalytic steps, namely the C-C coupling of phenol and pyruvate in the presence of ammonia, which leads to the corresponding tyrosine derivative, followed by deamination and decarboxylation. The biocatalytic transformation proceeded with high regioselectivity and afforded exclusively the desired para products. This method thus represents an environmentally friendly approach for the direct vinylation of readily available 2-, 3-, or 2,3-disubstituted phenols on preparative scale (0.5 mmol) that provides vinylphenols in high yields (65-83%).
