70719-39-0

Upstream product

• 3465-69-8 5,7-dimethoxyphthalide 
• 108-98-5 thiophenol 
• 70719-51-6 methyl 2,4-dimethoxy-6-<(phenylthio) methyl>-benzoate 

Downstream Products

• 111649-51-5 4-<2-(4-tetrahydropyranyloxybutyl)-1,3-dithian-2-yl>-1-methylbutyl-2,4-dimethoxy-6-(phenylthiomethyl) benzoate 
• 111649-53-7 4-<2-(4-methanesulfonyloxybutyl)-1,3-dithian-2-yl>-1-methylbutyl-2,4-dimethoxy-6-<(phenylthio) methyl> benzoate 
• 111649-56-0 4-<2-(4-methanesulfonyloxy butyl)-1,3-dioxalan-2-yl>-1-methylbutyl-2,4-dimethoxy-6-<(phenylthio) methyl> benzoate 
• 111649-54-8 9-methanesulfonyloxy-1-methyl-5-oxo-nonyl-2,4-dimethoxy-6-<(phenylthio) methyl> benzoate 
• 111649-58-2 2,4-Dimethoxy-6-phenylsulfanylmethyl-benzoic acid 4-[2-(4-iodo-butyl)-[1,3]dithian-2-yl]-1-methyl-butyl ester 
• 111649-52-6 2,4-Dimethoxy-6-phenylsulfanylmethyl-benzoic acid 4-[2-(4-hydroxy-butyl)-[1,3]dithian-2-yl]-1-methyl-butyl ester 
• 111649-55-9 2,4-Dimethoxy-6-phenylsulfanylmethyl-benzoic acid 9-hydroxy-1-methyl-5-oxo-nonyl ester 
• 73127-59-0 4-<2-(4-iodobutyl)-1,3-dioxalan-2-yl>-1-methylbutyl-2,4-dimethoxy-6-<(phenylthio) methyl> benzoate 
• 71787-00-3 2,4-Dimethoxy-6-phenylsulfanylmethyl-benzoyl chloride 
• 139219-43-5 1-Methyl-5-oxonon-8-enyl 2,4-Dimethoxy-6-(phenylthiomethyl)benzoate 

Relevant academic research and scientific papers

Divergent syntheses of resorcylic acid lactones: L-783277, LL-Z1640-2, and hypothemycin

The resorcylic acid lactones (RAL) are endowed with diverse biological activity ranging from transcription factor modulators (zearalenone and zearalenol) to HSP90 inhibitors (radicicol and pochonin D) and reversible (aigialomycin D) as well as irreversibl

SYNTHESIS OF (+/-)-ZEARALENONE

The aliphatic portion of (+/-)-zearalenone has been synthesised by a new simple route starting from 2,3-dihydropyran and 2-acetyl-γ-butyrolactone by employing dithiane for C-C bond formation.The final condensation of this segment with the aromatic part and subsequent transformations led to (+/-)-zearalenone.