70738-04-4

Basic information

• Product Name: Benzaldehyde, 2-iodo-3,6-dimethoxy-
• CAS NO: 70738-04-4
• Molecular Formula: C9H9IO3
• Molecular Weight: 292.073
• Mol File: 70738-04-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzaldehyde, 2-iodo-3,6-dimethoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzaldehyde, 2-iodo-3,6-dimethoxy-(70738-04-4)
• EPA Substance Registry System: Benzaldehyde, 2-iodo-3,6-dimethoxy-(70738-04-4)

Safety Data

• Hazardous Substances Data: 70738-04-4(Hazardous Substances Data)

Upstream product

• 93-02-7 2,5-dimethoxybenzaldehyde 
• 141058-36-8 2-(2',5'-dimethoxyphenyl)-1,3-dioxane 
• 71255-05-5 2-iodo-3,6-dimethoxybenzyl vinyl ether 
• 71255-03-3 2,5-dimethoxybenzyl vinyl ether 
• 33524-31-1 2,5-dimethoxybenzyl alcohol 
• 71255-06-6 2-iodo-3,6-dimethoxybenzyl alcohol 

Downstream Products

• 63160-44-1 2-hydroxymethyl-3-(3-methylbut-3-en-1-ynyl)benzene-1,4-diol 
• 63160-46-3 2,5-dihydroxy-6-(3-methylbut-3-en-1-ynyl)benzaldehyde 
• 73151-59-4 (7E,9E,11E)-aurocitrin 
• 81477-62-5 2-iodo-3-<(tert-butyldimethylsilyl)oxy>-6-hydroxybenzaldehyde 
• 81477-64-7 3-O-(tert-butyldimethylsilyl)frustulosin 
• 81477-61-4 2-iodo-3,6-bis<(tert-butyldimethylsilyl)oxy>benzaldehyde 
• 81477-68-1 2-iodo-3,6-bis<(tert-butyldimethylsilyl)oxy>cinnamaldehyde 
• 81477-63-6 bis(tert-butyldimethylsilyl)frustulosin 
• 81477-70-5 5-<2-iodo-3,6-bis(tert-butyldimethylsiloxy)phenyl>-2,4-pentadienal 
• 81477-65-8 1-<2-iodo-3,6-bis(tert-butyldimethylsiloxy)phenyl>-1,3,5-undecatriene 
• 81477-71-6 1-<2-iodo-3,6-bis(tert-butyldimethylsiloxy)phenyl>-1,3-undecadien-5-ol 

Relevant articles and documents

Ruthenium(0)-Catalyzed [4+2] Cycloaddition of Acetylenic Aldehydes with α-Ketols: Convergent Construction of Angucycline Ring Systems

Ruthenium(0) complexes modified by CyJohnPhos or RuPhos catalyze the successive C-C coupling of acetylenic aldehydes with α-ketols to form [4+2] cycloadducts as single diastereomers. This method enables convergent construction of type€...II polyketide ring systems of the angucycline class. Ringing with efficiency: Ruthenium(0) complexes modified by either CyJohnPhos or RuPhos catalyze the successive C-C coupling of acetylenic aldehydes with α-ketols to form [4+2] cycloadducts as single diastereomers. This method enables convergent construction of type€...II polyketide ring systems of the angucycline class.

Total Synthesis of Frustulosin and Aurocitrin

The regioselective total syntheses of the novel fungal antibiotics frustulosin (1) and aurocitrin (2) were accomplished from 3,6-dihydroxy-2-iodobenzaldehyde (10) which was prepared by a regiodirected metalation of 2,5-dimethylbenzyl vinyl ether to establish the 1,2,3,4-tetrasubstitution pattern of these compounds.The unsaturated side chains of these hydroquinone antibiotics were attached by using the iodo aldehyde functionalities.The structures of these antibiotics are confirmed by synthesis.