71255-06-6

Upstream product

• 33524-31-1 2,5-dimethoxybenzyl alcohol 
• 71255-05-5 2-iodo-3,6-dimethoxybenzyl vinyl ether 
• 71255-03-3 2,5-dimethoxybenzyl vinyl ether 

Downstream Products

• 70738-04-4 2-iodo-3,6-dimethoxybenzaldehyde 
• 63160-44-1 2-hydroxymethyl-3-(3-methylbut-3-en-1-ynyl)benzene-1,4-diol 
• 63160-46-3 2,5-dihydroxy-6-(3-methylbut-3-en-1-ynyl)benzaldehyde 
• 70738-05-5 2-iodo-3,6-dihydrobenzaldehyde 
• 73151-59-4 (7E,9E,11E)-aurocitrin 
• 81477-62-5 2-iodo-3-<(tert-butyldimethylsilyl)oxy>-6-hydroxybenzaldehyde 
• 81477-64-7 3-O-(tert-butyldimethylsilyl)frustulosin 
• 81477-61-4 2-iodo-3,6-bis<(tert-butyldimethylsilyl)oxy>benzaldehyde 
• 81477-68-1 2-iodo-3,6-bis<(tert-butyldimethylsilyl)oxy>cinnamaldehyde 
• 81477-63-6 bis(tert-butyldimethylsilyl)frustulosin 
• 81477-70-5 5-<2-iodo-3,6-bis(tert-butyldimethylsiloxy)phenyl>-2,4-pentadienal 
• 81477-65-8 1-<2-iodo-3,6-bis(tert-butyldimethylsiloxy)phenyl>-1,3,5-undecatriene 
• 81477-71-6 1-<2-iodo-3,6-bis(tert-butyldimethylsiloxy)phenyl>-1,3-undecadien-5-ol 

Relevant academic research and scientific papers

Total Synthesis of Frustulosin and Aurocitrin

The regioselective total syntheses of the novel fungal antibiotics frustulosin (1) and aurocitrin (2) were accomplished from 3,6-dihydroxy-2-iodobenzaldehyde (10) which was prepared by a regiodirected metalation of 2,5-dimethylbenzyl vinyl ether to establish the 1,2,3,4-tetrasubstitution pattern of these compounds.The unsaturated side chains of these hydroquinone antibiotics were attached by using the iodo aldehyde functionalities.The structures of these antibiotics are confirmed by synthesis.

2,5-Dimethoxybenzyl Alcohol: a Convenient Self-indicating Standard for the Determination of Organolithium Reagents

A method for the determination of organolithium reagent is described using 2,5-dimethoxybenzyl alcohol as a self-indicating primary standard.