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Usage

Uses

Used in Organic Synthesis:
Benzo[1,2-b:4,5-b]dipyrrole, 1,5-dihydro(8CI,9CI) is utilized as a key intermediate in the synthesis of various organic compounds. Its complex ring structure and unique chemical properties allow for the creation of novel molecules with specific functionalities, contributing to the advancement of organic chemistry.
Used in Materials Science:
In the field of materials science, Benzo[1,2-b:4,5-b]dipyrrole, 1,5-dihydro(8CI,9CI) is employed as a building block for the development of new materials with tailored properties. Its incorporation into polymers, coatings, or other materials can lead to improved performance characteristics, such as enhanced stability, conductivity, or optical properties.
Used in Pharmaceutical Research:
Benzo[1,2-b:4,5-b]dipyrrole, 1,5-dihydro(8CI,9CI) is of interest in pharmaceutical research due to its potential biological activity. Its unique structure may interact with biological targets, such as enzymes or receptors, leading to the development of new drugs with therapeutic potential. Further studies are required to explore its pharmacological properties and evaluate its efficacy in treating various diseases.
Overall, Benzo[1,2-b:4,5-b]dipyrrole, 1,5-dihydro(8CI,9CI) is a versatile molecule with a wide range of potential applications across different industries. Its complex structure and intriguing properties make it an exciting area of research and development, with the potential to contribute significantly to the fields of organic synthesis, materials science, and pharmaceuticals.

Upstream product

• 137601-30-0 1-(5-Acetyl-5H-pyrrolo[2,3-f]indol-1-yl)-2,2,2-trifluoro-ethanone 
• 16078-30-1 1-Acetyl-2,3-dihydro-1H-indole 
• 1141727-54-9 2,5-diethynyl-1,4-phenylenediamine 
• 82221-06-5 6-acetyl-3,6,7,8-tetrahydrobenzo<1,2-b:4,3-b'>dipyrrole-2-carboxylic acid, ethyl ester 
• 82221-05-4 2-ethoxycarbonyl-6,7-dihydro-1H,5H-pyrrolo<2,3-f>indole 
• 137601-28-6 N-(1-Acetyl-2,3-dihydro-1H-indol-5-yl)-N-(2,2-diethoxy-ethyl)-2,2,2-trifluoro-acetamide 
• 137601-29-7 1-acetyl-5-(trifluoroacetyl)-1,2,3,5-tetrahydropyrrolo<2,3-f>indole 
• 4993-96-8 1-(5-aminoindolin-1-yl)ethanone 
• 496-15-1 1-indoline 
• 712-32-3 1,4-Dimethyl-2,5-dinitrobenzol 
• 105518-48-7 6-acetyl-3,6,7,8-tetrahydrobenzo<1,2-b:4,3-b'>dipyrrole-2-carboxylic acid 

Downstream Products

• 88228-99-3 3,7-diphenylazo-1H,5H-pyrrolo(2,3-f)indole 
• 88222-96-2 3,7-bis(p-chlorophenylazo)-1H,5H-pyrrolo(2,3-f)indole 
• 84905-60-2 3,7-Bis(dimethylaminomethyl)-1H,5H-pyrrolo<2,3-f>indole dimethiodide 

Relevant academic research and scientific papers

Intramolecular cyclization of ortho-alkynylanilines by Rh(I)-catalyzed hydroamination to yield benzo(dipyrroles)

The methylene-bridged Rh(I) dicarbonyl complex, [Rh(bim) (CO)2+ BPh4-] (1) (bim = bis(N-methylimidazol-2-yl)methane), is an effective catalyst for the intramolecular hydroamination of selected ortho-alkynylanilines to give a range of benzo(dipyrroles).

Regioselectivity in electrophilic substitution of 5-aminoindoles and 5-aminoindolines: Synthesis of pyrrolo[3,2-e]indoles and isomeric pyrrolo[2,3-f]indoles

An FMO Theory prediction that 5-aminoindoles, 5, should react with electrophiles preferentially at C4 rather than at C6 whereas N1-acyl-5-aminoindolones, 6, should react preferentially at C6 rather than C4 is borne out experimentally by the synthesis of a pyrrolo[3,2-e]indole from 5 and pyrrolo[2,3-f]indoles from 6.

Expeditious Synthesis of Dihydrobenzo--, , and -dipyrroles

A simple, high-yield, two-step synthesis of the title compounds (1)-(3) is described, based on the catalytic reduction of the bis-enamines (4)-(6), in turn obtained by condensation of dimethylformamide diethyl acetal with the appropriate dinitro-xylene.

PYRROLOINDOLES. 6. NEW SYNTHESIS OF 1H,5H-PYRROLOINDOLE AND 3H,6H-PYRROLOINDOLE

Ethyl pyruvate 1-acetyl-5-indolinylhydrazone was obtained by diazotization of 1-acetyl-5-aminoindoline with subsequent reduction of the diazonium salt and condensation of the hydrazine with ethyl pyruvate.A mixture of hydrogenated derivatives of linear and angular pyrroloindoles is formed as a result of cyclization of the hydrazone in polyphosphoric acid esters.Subsequent hydrolysis, decarboxylation, and dehydrogenation lead to 1H,5H-pyrroloindole and 3H,6H-pyrroloindole.