70769-70-9

Basic information

• Product Name: 2-Propanone, 1,3-bis(4-methylphenyl)-
• CAS NO: 70769-70-9
• Molecular Formula: C17H18O
• Molecular Weight: 238.329
• Mol File: 70769-70-9.mol

Chemical Properties

• CAS DataBase Reference: 2-Propanone, 1,3-bis(4-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propanone, 1,3-bis(4-methylphenyl)-(70769-70-9)
• EPA Substance Registry System: 2-Propanone, 1,3-bis(4-methylphenyl)-(70769-70-9)

Safety Data

• Hazardous Substances Data: 70769-70-9(Hazardous Substances Data)

Upstream product

• 109397-62-8 1,3-di-p-tolyl-propan-2-ol 
• 104-81-4 4-Methylbenzyl bromide 
• 201230-82-2 carbon monoxide 
• 22535-04-2 p-methylphenylacetyl bromide 
• 38622-91-2 [(p-methylphenyl)sulfonylmethyl]isonitrile 
• 67-64-1 acetone 
• 108-88-3 toluene 
• 25726-04-9 phenylglyoxylyl chloride 
• 104-82-5 4-Methylbenzyl chloride 
• 4755-77-5 Ethyl oxalyl chloride 
• 622-47-9 4-tolylacetic acid 

Downstream Products

• 102374-82-3 1,5-di-p-tolyl-3,7-diaza-bicyclo[3.3.1]nonan-9-one 
• 38268-18-7 2,5-bis-(4-methylphenyl)-3,4-diphenylcyclopenta-2,4-dienone 
• 31635-75-3 2,3,4,5-tetra(4-methylphenyl)cyclopenta-2,4-dien-1-one 
• 83808-71-3 1,3-Di-p-tolylcyclopentaceanthrylene-2(H)-one 
• 538-39-6 1,2-di-p-tolylethane 
• 104-82-5 4-Methylbenzyl chloride 
• 81979-66-0 2,6-Di-p-tolyl-cyclohexanone 
• 501034-28-2 1,3-dibromo-1,3-di-p-tolyl-propan-2-one 
• 717105-86-7 2,5-bis(p-tolyl)-3,4-bis{4-[2',3',4',5'-tetra(p-tolyl)]biphenylyl}cyclopentadienone 
• 1319733-01-1 5,6-diphenyl-4,7-di-p-tolylisoindoline-1,3-dione 
• 1319733-08-8 7,11-di-p-tolyl-8H-acenaphtho[1,2-f]isoindole-8,10(9H)-dione 

Relevant articles and documents

Lanthanide Silylamide-Catalyzed Synthesis of Pyrano[2,3- b]indol-2-ones

A lanthanide silylamide-catalyzed tandem reaction of isatins, diethyl phosphite, and 2,3-diarylcyclopropenones has been developed. A series of pyrano[2,3-b]indol-2-ones were synthesized in high yields. The cooperation of the Lewis acidity of the lanthanide center and the Bronsted basicity of the N(SiMe3)2 anion may be the key factor affecting the catalytic activity of lanthanide amides.

Fully Substituted Conjugate Benzofuran Core: Multiyne Cascade Coupling and Oxidation of Cyclopropenone

An unprecedented C═C double bond cleavage of cyclopropenone and dioxygen activation by multiyne cascade coupling has been developed. This chemistry provides a novel, simple, and efficient approach to synthesize fully substituted conjugate benzofuran derivatives from simple substrates under mild conditions. The density functional theory (DFT) calculations reveal that the unique homolytic cleavages of cyclopropenone and molecular oxygen are crucial to the success of this reaction.

Iron-Catalyzed One-Step Synthesis of Isothiazolone/1,2-Selenazolone Derivatives via [3+1+1] Annulation of Cyclopropenones, Anilines, and Elemental Chalcogens

Described herein is the one-step synthesis of isothiazolone/1,2-selenazolone derivatives via [3+1+1] cycloaddition of cyclopropenone derivatives, anilines, and elemental chalcogens. The cascade reaction involves the C?S, C?N, and N?S bond formation along with the cleavage of C?C bond. Both anilines and cyclopropenones are tolerated and give the corresponding products in 28–73% yields. (Figure presented.).

Catalytic Asymmetric (3 + 3) Cycloaddition of Oxyallyl Zwitterions with α-Diazomethylphosphonates

The unique structure of oxyallyls represents a significant challenge for their catalytic asymmetric applications. Herein, an unprecedented chiral imidodiphosphoric acid-catalytic enantioselective (3 + 3) cycloaddition between oxyallyl zwitterions generate

Cascade Ring-Opening Dual Halogenation of Cyclopropenones with Saturated Oxygen Heterocycles

Represented is a CuX2- or I2-promoted ring-opening dual halogenation of cyclopropenones with saturated oxygen heterocycles, providing an efficient method for the synthesis of 3-haloacrylates. The ring-opening reaction enables the construction of two C–X (X = Cl, Br, or I) bonds and a C–O bond as well as the cleavage of two C–O bonds and a C–C bond in a single step. This protocol is highly atom economical, has an excellent substrate scope, and exhibits the ability for gram-scale reaction.

Rh(III)-Catalyzed [3 + 3] Annulation Reaction of Cyclopropenones and Sulfoxonium Ylides toward Trisubstituted 2-Pyrones

A new Rh(III)-catalyzed [3 + 3] annulation reaction between cyclopropenones and β-ketosulfoxonium ylides has been reported, enabling metal carbene insertion to access a wide range of trisubstituted 2-pyrones with moderate to excellent yields via C-C single-bond cleavage, in which sulfoxonium ylides serve as potential safe precursors of metal carbenes. This reaction occurred under redox-neutral conditions with a broad substrate scope.

Thianthrenation-enabled α-arylation of carbonyl compounds with arenes

The Pd-catalyzed α-arylation of carbonyl compounds with simple arenes enabled by site-selective thianthrenation has been demonstrated. This onepot process using thianthrenium salts as the traceless arylating reagents features mild conditions and a broad substrate scope. In addition, this protocol could also tolerate the heterocyclic carbonyl compounds and complex bioactive molecules, which is appealing for medicinal chemistry.

Pentaphenylmethylbenzene-containing difluorine monomer, preparation method and application thereof in polyaryletherketone functional membranes

The invention relates to a pentaphenylmethylbenzene-containing difluorine monomer, a preparation method and application thereof in polyaryletherketone functional membranes, and belongs to the technical field of polymer materials and preparation thereof. T

Organocatalytic Regiodivergent C?C Bond Cleavage of Cyclopropenones: A Highly Efficient Cascade Approach to Enantiopure Heterocyclic Frameworks

Here a highly efficient cascade approach is reported that combines a cycloaddition reaction with a regioselective strain-release process to afford diverse heterocyclic frameworks through bifunctional catalysis. The cooperation of hydrogen-bonding network activation and a regiodivergent strain-assisted effect is the key to promoting this complex chemical transformation, leading to the generation of two different ring systems in high yields with excellent stereoselectivities. The reaction proceeded by a mechanism involving a “spring-loaded” intermediate with switchable C?C bond cleavages achieved by controllable ring-strain release. This reaction was also amenable to gram scale synthesis with only 0.1 mol % catalyst loading.

Organocatalyzed [3 + 2] Annulation of Cyclopropenones and β-Ketoesters: An Approach to Substituted Butenolides with a Quaternary Center

An unprecedented organocatalyzed [3 + 2] annulation of cyclopropenones and β-ketoesters has been developed. This reaction provides a direct approach to highly substituted butenolides with a quaternary center in moderate to good yields. The preliminary mechanism study verified that the enol intermediate is crucial to the reaction outcome and the intermolecular esterification and intramolecular Michael addition process were involved.